Risk of carcinoma after subsequent excision of benign papilloma initially diagnosed with an ultrasound (US)-guided 14-gauge core needle biopsy: a prospective observational study.
Objective: To prospectively determine the upgrade rate following surgery in benign papilloma initially diagnosed at ultrasound (US)-guided 14-gauge gun biopsy.Methods: A total of 128 benign papillomas were diagnosed in 114 patients after a US-guided biopsy. Surgical excision was recommended where th...
| Publicado en: | European Radiology Vol. 20; no. 5; pp. 1093 - 1101 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
May2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105167266&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105167266 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: May2010 vid: 20 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105167266 49024282 NLM19890638 2010618424 10.1007/s00330-009-1649-2 NLM19890638 105167266 ppf: 1093 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Risk of carcinoma after subsequent excision of benign papilloma initially diagnosed with an ultrasound (US)-guided 14-gauge core needle biopsy: a prospective observational study. aug: au: Chang JM Moon WK Cho N Han W Noh DY Park IA Jung EJ Chang, Jung Min Moon, Woo Kyung Cho, Nariya Han, Wonshik Noh, Dong-Young Park, In-Ae Jung, Eun-Jung affil: Department of Radiology and Clinical Research Institute, Seoul National University Hospital and the Institute of Radiation Medicine, Seoul National University Medical Research Center, Chongno-gu, Seoul, Republic of Korea sug: subj: Biopsy, Needle Methods Breast Neoplasms Pathology Carcinoma in Situ Pathology Carcinoma, Papillary Pathology Ultrasonography Adult Aged Breast Neoplasms Surgery Breast Neoplasms Ultrasonography Carcinoma in Situ Surgery Carcinoma in Situ Ultrasonography Carcinoma, Papillary Surgery Carcinoma, Papillary Ultrasonography Chi Square Test Female Human Logistic Regression Middle Age Neoplasm Invasiveness Neoplasm Staging Prospective Studies Relative Risk Risk Assessment Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female ab: Objective: To prospectively determine the upgrade rate following surgery in benign papilloma initially diagnosed at ultrasound (US)-guided 14-gauge gun biopsy.Methods: A total of 128 benign papillomas were diagnosed in 114 patients after a US-guided biopsy. Surgical excision was recommended where the biopsy indicated benign papilloma, regardless of imaging findings. The upgrade rate to 'atypical' and 'malignancy' was measured on a per-lesion basis. We analysed potential associations between clinical presentation, lesion variables and the results of surgical excision (using logistic regression).Results: Of the 114 patients, 87 eventually underwent surgery: among the 100 supposed benign papillomas, surgical excision revealed fibrocystic change or no residual lesion in nine cases, intraductal papilloma in 74, atypical papilloma in 13, papillary ductal carcinoma in situ (DCIS) in three and one invasive papillary carcinoma. The upgrade rate for an atypical papilloma or papilloma with adjacent foci of atypical ductal hyperplasia (ADH) and malignancy was 13% (95% CI = 7.1-21.2%) and 4% (95% CI = 1.1-9.9%), respectively. The mean lesion size (P = 0.041) was significantly larger when lesions were upgraded to malignancy. Other features were not significantly associated with pathological underestimation (P > 0.05).Conclusion: Surgical excision should be considered for benign intraductal papillomas above 1.5 cm in size. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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