Automated computer-aided stenosis detection at coronary CT angiography: initial experience.

Objective: To evaluate the performance of a computer-aided algorithm for automated stenosis detection at coronary CT angiography (cCTA).Methods: We investigated 59 patients (38 men, mean age 58 +/- 12 years) who underwent cCTA and quantitative coronary angiography (QCA). All cCTA data sets were anal...

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Publicado en:European Radiology Vol. 20; no. 5; pp. 1160 - 1168
Autores principales: Arnoldi E, Gebregziabher M, Schoepf UJ, Goldenberg R, Ramos-Duran L, Zwerner PL, Nikolaou K, Reiser MF, Costello P, Thilo C, Arnoldi, Elisabeth, Gebregziabher, Mulugeta, Schoepf, U Joseph, Goldenberg, Roman, Ramos-Duran, Luis, Zwerner, Peter L, Nikolaou, Konstantin, Reiser, Maximilian F, Costello, Philip, Thilo, Christian
Formato: research Journal Article
Publicado: Springer Nature May2010
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Automated computer-aided stenosis detection at coronary CT angiography: initial experience.
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          Arnoldi E
          Gebregziabher M
          Schoepf UJ
          Goldenberg R
          Ramos-Duran L
          Zwerner PL
          Nikolaou K
          Reiser MF
          Costello P
          Thilo C
          Arnoldi, Elisabeth
          Gebregziabher, Mulugeta
          Schoepf, U Joseph
          Goldenberg, Roman
          Ramos-Duran, Luis
          Zwerner, Peter L
          Nikolaou, Konstantin
          Reiser, Maximilian F
          Costello, Philip
          Thilo, Christian
        affil: Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Drive, MSC 226, Charleston, SC 29401, USA
      sug:
        subj:
          Coronary Angiography Methods
          Coronary Stenosis Radiography
          Information Science Methods
          Radiographic Image Interpretation, Computer-Assisted Methods
          Tomography, X-Ray Computed Methods
          Algorithms
          Female
          Human
          Logistic Regression
          Male
          Middle Age
          Sensitivity and Specificity
          Software
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: To evaluate the performance of a computer-aided algorithm for automated stenosis detection at coronary CT angiography (cCTA).Methods: We investigated 59 patients (38 men, mean age 58 +/- 12 years) who underwent cCTA and quantitative coronary angiography (QCA). All cCTA data sets were analyzed using a software algorithm for automated, without human interaction, detection of coronary artery stenosis. The performance of the algorithm for detection of stenosis of 50% or more was compared with QCA.Results: QCA revealed a total of 38 stenoses of 50% or more of which the algorithm correctly identified 28 (74%). Overall, the automated detection algorithm had 74%/100% sensitivity, 83%/65% specificity, 46%/58% positive predictive value, and 94%/100% negative predictive value for diagnosing stenosis of 50% or more on per-vessel/per-patient analysis, respectively. There were 33 false positive detection marks (average 0.56/patient), of which 19 were associated with stenotic lesions of less than 50% on QCA and 14 were not associated with an atherosclerotic surrogate.Conclusion: Compared with QCA, the automated detection algorithm evaluated has relatively high accuracy for diagnosing significant coronary artery stenosis at cCTA. If used as a second reader, the high negative predictive value may further enhance the confidence of excluding significant stenosis based on a normal or near-normal cCTA study.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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