Accuracy of rapid urease test in diagnosing Helicobacter pylori infection in patients using NSAIDs.
Background/Aim: This study aimed to determine the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on the results of rapid urease test (RUT). Patients and Methods: The study evaluated 210 consecutive patients for the diagnosis of Helicobacter pylori (H. pylori) infection. They were divided in...
| Publicado en: | Saudi Journal of Gastroenterology Vol. 16; no. 2; pp. 110 - 113 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Apr2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105168990&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105168990 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13193767 322P jtl: Saudi Journal of Gastroenterology issn: 13193767 maglogo: N pubinfo: dt: Apr2010 vid: 16 iid: 2 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 105168990 2010620498 10.4103/1319-3767.61238 NLM20339181 105168990 ppf: 110 ppct: 3 formats: tig: atl: Accuracy of rapid urease test in diagnosing Helicobacter pylori infection in patients using NSAIDs. aug: au: Foroutan M Loloei B Irvani S Azargashb E affil: Department of Gastroenterology, Shahid Beheshti University of Medical Sciences, Tehran, Iran; swt_f@yahoo.com sug: subj: Antiinflammatory Agents, Non-Steroidal Helicobacter Infections Helicobacter Infections Diagnosis Helicobacter Pylori Validity Demography Human Iran Prevalence Sensitivity and Specificity ab: Background/Aim: This study aimed to determine the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on the results of rapid urease test (RUT). Patients and Methods: The study evaluated 210 consecutive patients for the diagnosis of Helicobacter pylori (H. pylori) infection. They were divided into case and control groups based on history of NSAID use (n=70 each). Two biopsy specimens were collected from antrum and corpus of stomach during endoscopy and sent for rapid urease testing and histopathology. Sensitivity, specificity, and accuracy rate of RUT test were compared against histology. Results: The average age was 55.2±12.9 and 43.3±12.1 years in the case and control groups, respectively. Among NSAID users, RUT sensitivity, specificity and accuracy rate were all 100%. The sensitivity, specificity and accuracy rate of RUT in patients without history of NSAID use were 97.37, 98.57 and 98.14%, respectively. The overall sensitivity, specificity and accuracy rate of RUT were 98.57, 99.29, and 99.04%, respectively. Conclusion: Our study shows that sensitivity, specificity and accuracy rate of RUT are not affected by NSAID use. Rapid urease test remains a reliable test for diagnosis of H. pylori in patients on NSAIDs. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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