Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y(12) receptor antagonist, in healthy subjects.
Purpose: Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist in development for reduction of clinical thrombotic events in patients with acute coronary syndromes. The purpose of our studies was to determine the effect of single-ascending doses of ticagrelor in healt...
| Published in: | European Journal of Clinical Pharmacology Vol. 66; no. 5; pp. 487 - 497 |
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| Main Authors: | , |
| Format: | clinical trial research tables/charts Journal Article |
| Published: |
Springer Nature
May2010
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| Online Access: | View this record in EBSCOhost |