Factors that impact choice of antidepressant treatment in medically complex patients.

In medically complex patients with multiple comorbid illnesses who require concomitant medications, selecting the optimal antidepressant (ie, low risk of adverse effects and/or pharmacokinetic interactions) for an individual patient is critical for positive long-term patient outcomes. The serotonin-...

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Publicado en:CNS Spectrums: The International Journal of Neuropsychiatric Medicine Vol. 14; pp. 20 - 28
Autores principales: Dago PL, Dago, Pedro Luis
Formato: case study Journal Article
Publicado: Cambridge University Press Dec2009 Supplement
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Factors that impact choice of antidepressant treatment in medically complex patients.
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        au:
          Dago PL
          Dago, Pedro Luis
        affil: Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine of Northwestern University, 446 East Ontario Avenue, Chicago, IL 60611-3008, USA
      sug:
        subj:
          Antidepressive Agents Therapeutic Use
          Depression Drug Therapy
          Serotonin Uptake Inhibitors Therapeutic Use
          Adult
          Antidepressive Agents Adverse Effects
          Antidepressive Agents Pharmacokinetics
          Cardiovascular Diseases Chemically Induced
          Decision Making
          Kidney Diseases Chemically Induced
          Liver Diseases Etiology
          Male
          Serotonin Uptake Inhibitors Adverse Effects
          Serotonin Uptake Inhibitors Pharmacokinetics
          Treatment Outcomes
          Adult: 19-44 years
          Male
      ab: In medically complex patients with multiple comorbid illnesses who require concomitant medications, selecting the optimal antidepressant (ie, low risk of adverse effects and/or pharmacokinetic interactions) for an individual patient is critical for positive long-term patient outcomes. The serotonin-norepinephrine reuptake inhibitors (SNRls) are increasingly being used as first-line treatment for major depressive disorder (MDD) and may prove beneficial for treatment of medically complex patients.Thus, it is key for clinicians to evaluate the differences in the pharmacokinetic and tolerability profiles of the SNRI class of antidepressants, evaluating differences both within the class and compared with other antidepressants used to treat MDD.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
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