Brief report: Under-representation of African Americans in autism genetic research: a rationale for inclusion of subjects representing diverse family structures.

African American children with autism are seriously under-represented in existing genetic registries and biomedical research studies of autism. We estimated the number of African American children with autism in the St. Louis region using CDC surveillance data and present the outcomes of a concerted...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 40; no. 5; pp. 633 - 640
Autores principales: Hilton CL, Fitzgerald RT, Jackson KM, Maxim RA, Bosworth CC, Shattuck PT, Geschwind DH, Constantino JN
Formato: research tables/charts Journal Article
Publicado: Springer Nature May2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2010
      vid: 40
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      pub: Springer Nature
      place: New York, New York
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        atl: Brief report: Under-representation of African Americans in autism genetic research: a rationale for inclusion of subjects representing diverse family structures.
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          Hilton CL
          Fitzgerald RT
          Jackson KM
          Maxim RA
          Bosworth CC
          Shattuck PT
          Geschwind DH
          Constantino JN
        affil: Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, St Louis, MO 63110 USA
      sug:
        subj:
          Autism Spectrum Disorder
          Minority Groups
          Research Subject Recruitment
          African Americans
          Funding Source
          Human
          Missouri
          Nonexperimental Studies
          Prospective Studies
          Record Review
          Registries, Disease
      ab: African American children with autism are seriously under-represented in existing genetic registries and biomedical research studies of autism. We estimated the number of African American children with autism in the St. Louis region using CDC surveillance data and present the outcomes of a concerted effort to enroll approximately one-third of that population into either of two large national genetic autism registries. The results revealed that even after traditional barriers to research participation were addressed and all contacted families expressed a willingness to participate, 67% of the reachable families were disqualified from participation because of family structure alone. Comprehensive efforts-including expansion of eligibility to families of diverse structure-are warranted to facilitate the inclusion of African American children in biomedical research.
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        tables/charts
        Journal Article
      ougenre: Article
    language: English
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