Effect of plasma uric acid on pharmacokinetics of cyclosporine A in living-related renal transplant recipients and pharmacokinetic study in rats with experimental hyperuricaemia.

Objectives: Renal transplant recipients are thought to have an increased risk of hyperuricaemia (HU); therefore, the effects of plasma uric acid (UA) on the pharmacokinetics (PK) of cyclosporine A (CyA), an immunosuppressant, in renal transplant recipients and experimental animals were investigated....

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Publicado en:Journal of Clinical Pharmacy & Therapeutics Vol. 35; no. 3; pp. 323 - 333
Autores principales: Sugioka N, Takai M, Yoshida K, Yasuda K, Fukushima K, Kokuhu T, Okamoto M, Yoshimura N, Takada K
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Jun2010
Acceso en línea:Ver este registro en EBSCOhost