Dual-isotope acquisition for CT-SPECT registration of infection studies.
The registration of CT and NM images can enhance patient diagnosis since it allows for the fusion of anatomical and functional information as well as attenuation correction of NM images. However, irrespective of the methods used, registration accuracy depends heavily on the characteristics of the in...
| Publicado en: | Journal of Digital Imaging Vol. 23; no. 3; pp. 258 - 268 |
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| Autores principales: | , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105202695&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105202695 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08971889 DOQ jtl: Journal of Digital Imaging issn: 08971889 maglogo: N pubinfo: dt: Jun2010 vid: 23 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105202695 105202695 2010656983 10.1007/s10278-008-9171-7 NLM19137374 105202695 ppf: 258 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Dual-isotope acquisition for CT-SPECT registration of infection studies. aug: au: Tang L Hamarneh G Celler A affil: Medical Image Analysis Lab, Simon Fraser University, Burnaby, BC, Canada V5A 1S6. sug: subj: Radiographic Image Enhancement Tomography, Emission-Computed, Single-Photon Tomography, X-Ray Computed Algorithms Analysis of Variance Funding Source Human Radiographic Image Interpretation, Computer-Assisted Validation Studies ab: The registration of CT and NM images can enhance patient diagnosis since it allows for the fusion of anatomical and functional information as well as attenuation correction of NM images. However, irrespective of the methods used, registration accuracy depends heavily on the characteristics of the input images and the degree of similarity between them. This poses a challenge for registering CT and NM images as they may have very different characteristics. To address the particular problem of CT and In-111 SPECT registration, we propose to perform a dual-isotope study which involves an additional injection of Tc-99m MDP to generate two inherently registered images: In-111 SPECT and Tc-99m SPECT. As skeletal structures are visible in both CT and Tc-99m SPECT, performing registration of these images may be much more effective. The very same spatial transformation derived can be immediately applied to complete the registration of CT and the corresponding In-111 SPECT. Accordingly, we hypothesize that the registration of CT and Tc-99m SPECT can be more accurately performed than the registration of CT and In-111 SPECT and seek to compare the accuracies between the aforementioned registrations. In this paper, we have collected three clinical datasets, with the ground-truth transformations known, and tested the proposed approach by using a mutual information-based algorithm to solve for the rigid/non-rigid misalignments introduced to them. Based on the results of our experiments, we conclude that registration using Tc-99m SPECT can achieve 100% success rate, and is thus much more superior to the registration using In-111 SPECT, which at best, achieves only 38% success rate. Clearly, the introduction of a dual-isotope acquisition can substantially improve the registration of SPECT and CT images. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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