Single-dose, multiple-dose, and population pharmacokinetics of pantoprazole in neonates and preterm infants with a clinical diagnosis of gastroesophageal reflux disease (GERD)

The pharmacokinetic profile of pantoprazole granules was assessed in neonates and preterm infants with gastroesophageal reflux disease (GERD) in a multicenter, randomized, open-label trial. Patients were randomly assigned to either the pantoprazole 1.25 mg (approx. 0.6 mg/kg) or 2.5 mg (approx. 1.2-...

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Bibliographic Details
Published in:European Journal of Clinical Pharmacology Vol. 66; no. 6; pp. 555 - 562
Main Authors: Ward R, Tammara B, Sullivan S, Stewart D, Rath N, Meng X, Maguire M, Comer G
Format: clinical trial research Journal Article
Published: Springer Nature Jun2010
Online Access:View this record in EBSCOhost