Molecular surface mesh generation by filtering electron density map.

Bioinformatics applied to macromolecules are now widely spread and in continuous expansion. In this context, representing external molecular surface such as the Van derWaals Surface or the Solvent Excluded Surface can be useful for several applications. We propose a fast and parameterizable algorith...

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Publicado en:International Journal of Biomedical Imaging pp. 9p - 10
Autores principales: Giard J, Macq B
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 2010
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: International Journal of Biomedical Imaging
      issn: 16874188
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    pubinfo:
      dt: 2010
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        105205303
        2010659823
        10.1155/2010/923780
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        105205303
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        atl: Molecular surface mesh generation by filtering electron density map.
      aug:
        au:
          Giard J
          Macq B
        affil: Communications and Remote Sensing Laboratory, Catholic University of Louvain, B-1348 Louvain-la-Neuve, Belgium.
      sug:
        subj:
          Bioinformatics
          Proteins Analysis
          Algorithms
          Comparative Studies
          Funding Source
          Human
          Image Processing, Computer Assisted
          Validation Studies
      ab: Bioinformatics applied to macromolecules are now widely spread and in continuous expansion. In this context, representing external molecular surface such as the Van derWaals Surface or the Solvent Excluded Surface can be useful for several applications. We propose a fast and parameterizable algorithm giving good visual quality meshes representing molecular surfaces. It is obtained by isosurfacing a filtered electron densitymap. The densitymap is the result of the maximumof Gaussian functions placed around atom centers. This map is filtered by an ideal low-pass filter applied on the Fourier Transform of the density map. Applying the marching cubes algorithm on the inverse transform provides a mesh representation of the molecular surface.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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