Pyoderma gangraenosum after cesarean delivery.

Objective: Presentation of pyoderma gangraenosum (PG) as an important differential diagnosis for wound healing disorders after cesarian section. Adequate therapeutic regimens are discussed. Case report: A 39-year-old woman developed a PG after cesarean section. A treatment with prednisolone and cycl...

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Bibliographic Details
Published in:Clinical Medicine: Dermatology no. 2; pp. 23 - 27
Main Authors: Pauser S, Goerge T, Eickelmann M, Gaubitz M, Luger TA, Steinhoff M
Format: case study pictorial Journal Article
Published: Sage Publications Inc. 2009
Online Access:View this record in EBSCOhost
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Summary:Objective: Presentation of pyoderma gangraenosum (PG) as an important differential diagnosis for wound healing disorders after cesarian section. Adequate therapeutic regimens are discussed. Case report: A 39-year-old woman developed a PG after cesarean section. A treatment with prednisolone and cyclosporine A was started. Within three days of treatment, the inflammatory process was significantly reduced. Serological inflammatory markers and fever dropped to normal levels. Due to the development of a pronounced arterial hypertension, dapsone was additionally applied to reduce glucocorticoids and cyclosporine A doses. Rapid normalisation of blood pressure without aggravation. Modern wound dressings helped to rapidly establish granulation and reepithelialization. The immense ulceration completely healed after six months of therapy. Conclusion: PG is a potentially lethal disease and must be considered as an important differential diagnosis after abdominal surgery and cesarean section. Modern systemic and topical treatments help to treat PG successfully.