Innovative uses of thalidomide.
Thalidomide is approved for treating erythema nodosum leprosum and multiple myeloma, but it has also emerged as a useful treatment option for many refractory dermatologic disorders. Some of the innovative but off-label uses of thalidomide include aphthous stomatitis, Behçet's disease, lupus erythema...
| Publicado en: | Dermatologic Clinics Vol. 28; no. 3; pp. 577 - 587 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
W B Saunders
2010 Jul
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105217789&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105217789 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07338635 DO3 jtl: Dermatologic Clinics issn: 07338635 maglogo: N pubinfo: dt: 2010 Jul vid: 28 iid: 3 pid: 1351 pub: W B Saunders place: Philadelphia, Pennsylvania artinfo: ui: 105217789 2010674970 10.1016/j.det.2010.03.003 NLM20510766 105217789 ppf: 577 ppct: 10 formats: tig: atl: Innovative uses of thalidomide. aug: au: Chen M Doherty SD Hsu S affil: Department of Dermatology, Baylor College of Medicine, BCM Debakey Building M220, One Baylor Plaza, Mail Stop BCM368, Houston, TX 77030, USA. sug: subj: Leprostatic Agents Therapeutic Use Prescriptions, Drug Skin Diseases Drug Therapy Thalidomide Therapeutic Use Experimental Studies Female Leprostatic Agents Adverse Effects Leprostatic Agents Contraindications Leprostatic Agents Pharmacodynamics Male Thalidomide Adverse Effects Thalidomide Contraindications Thalidomide Pharmacodynamics Female Male ab: Thalidomide is approved for treating erythema nodosum leprosum and multiple myeloma, but it has also emerged as a useful treatment option for many refractory dermatologic disorders. Some of the innovative but off-label uses of thalidomide include aphthous stomatitis, Behçet's disease, lupus erythematosus, prurigo nodularis, sarcoidosis, actinic prurigo, graft-versus-host disease, Langerhans cell histiocytosis, erythema multiforme, lichen planus, Kaposi sarcoma, Jessner lymphocytic infiltrate, uremic pruritus, pyoderma gangrenosum, scleroderma, scleromyxedema, and necrobiosis lipoidica. This article reviews the background, pharmacology, and innovative uses of thalidomide in dermatology.Copyright © 2010 by Elsevier Inc. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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