Atrial fibrillation organization: quantification of propofol effects.
The effect of conventional i.v. anaesthetic agents on atrial fibrillation (AF) dynamics has not been fully addressed. We aim to evaluate whether the most frequently used intravenous anaesthetic agent, propofol, modifies AF organization parameters. Multiple and simultaneous intraatrial bipolar record...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 47; no. 3; pp. 333 - 342 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Mar2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105219815&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105219815 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Mar2009 vid: 47 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105219815 NLM19018581 2010207060 10.1007/s11517-008-0421-0 NLM19018581 105219815 ppf: 333 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Atrial fibrillation organization: quantification of propofol effects. aug: au: Cervigón R Moreno J Sánchez C Reilly RB Villacastín J Millet J Castells F Cervigón, Raquel Moreno, Javier Sánchez, César Reilly, Richard B Villacastín, Julián Millet, José Castells, Francisco affil: Escuela Universitaria Politécnica, Campus Universitario, Innovation in Bioengineering Research Group (IBIG), DIEEAC, UCLM, Camino del Pozuelo sn, 16071 Cuenca, Spain sug: subj: Anesthetics, Intravenous Pharmacodynamics Atrial Fibrillation Physiopathology Propofol Pharmacodynamics Adult Aged Electrocardiography Methods Physics Female Heart Atrium Drug Effects Heart Atrium Physiopathology Male Middle Age Models, Biological Signal Processing, Computer Assisted Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: The effect of conventional i.v. anaesthetic agents on atrial fibrillation (AF) dynamics has not been fully addressed. We aim to evaluate whether the most frequently used intravenous anaesthetic agent, propofol, modifies AF organization parameters. Multiple and simultaneous intraatrial bipolar recordings from 27 patients in AF were analyzed before and after infusing a propofol bolus. Signal organization parameters were determined using time and frequency domain analysis. Non-linear analysis was also performed to determine signal entropy. Linear analysis showed that AF becomes more organized in right atrial recordings after infusing propofol, increasing interelectrode correlation (difference of 0.017 +/- 0.005), with the contrary effect on the left atrial dipoles (difference of -0.015 +/- 0.009, p = 0.008). Entropy analysis showed similar findings, achieving a statistical significance of p = 0.001 with Shannon Entropy. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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