Spread of Cryptococcus gattii into Pacific Northwest region of the United States.

Cryptococcus gattii has emerged as a human and animal pathogen in the Pacific Northwest. First recognized on Vancouver Island, British Columbia, Canada, it now involves mainland British Columbia, and Washington and Oregon in the United States. In Canada, the incidence of disease has been one of the...

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Publicado en:Emerging Infectious Diseases Vol. 15; no. 8; pp. 1185 - 1192
Autores principales: Datta K, Bartlett KH, Baer R, Byrnes E, Galanis E, Heitman J, Hoang L, Leslie MJ, MacDougall L, Magill SS, Morshed MG, Marr KA, Datta, Kausik, Bartlett, Karen H, Baer, Rebecca, Byrnes, Edmond, Galanis, Eleni, Heitman, Joseph, Hoang, Linda, Leslie, Mira J
Formato: review Journal Article
Publicado: Centers for Disease Control & Prevention (CDC) Aug2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2009
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      pub: Centers for Disease Control & Prevention (CDC)
      place: Atlanta, Georgia
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        10.3201/eid1508.081384
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        atl: Spread of Cryptococcus gattii into Pacific Northwest region of the United States.
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          Datta K
          Bartlett KH
          Baer R
          Byrnes E
          Galanis E
          Heitman J
          Hoang L
          Leslie MJ
          MacDougall L
          Magill SS
          Morshed MG
          Marr KA
          Datta, Kausik
          Bartlett, Karen H
          Baer, Rebecca
          Byrnes, Edmond
          Galanis, Eleni
          Heitman, Joseph
          Hoang, Linda
          Leslie, Mira J
        affil: Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
      sug:
        subj:
          Communicable Diseases Epidemiology
          Cryptococcosis Epidemiology
          Animals
          British Columbia
          Communicable Diseases
          Cryptococcosis
          Cryptococcus Classification
          Cryptococcus
          Disease Outbreaks
          Ecosystem
          Environmental Microbiology
          Northwestern United States
          Population Surveillance
          Public Health
      ab: Cryptococcus gattii has emerged as a human and animal pathogen in the Pacific Northwest. First recognized on Vancouver Island, British Columbia, Canada, it now involves mainland British Columbia, and Washington and Oregon in the United States. In Canada, the incidence of disease has been one of the highest worldwide. In the United States, lack of cryptococcal species identification and case surveillance limit our knowledge of C. gattii epidemiology. Infections in the Pacific Northwest are caused by multiple genotypes, but the major strain is genetically novel and may have emerged recently in association with unique mating or environmental changes. C. gattii disease affects immunocompromised and immunocompetent persons, causing substantial illness and death. Successful management requires an aggressive medical and surgical approach and consideration of potentially variable antifungal drug susceptibilities. We summarize the study results of a group of investigators and review current knowledge with the goal of increasing awareness and highlighting areas where further knowledge is required.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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