MR-lymphangiography at 3.0 T--a feasibility study.

The purpose of this study was to establish and evaluate contrast-enhanced MR-lymphangiography (MRL) at 3.0 T for detection and visualization of abnormalities of the peripheral lymphatic system. Sixteen patients were examined with a highly resolved isotropic T1w-3D-GRE-(FLASH) sequence (TR 3.76 ms/TE...

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Publicado en:European Radiology Vol. 19; no. 11; pp. 2771 - 2779
Autores principales: Notohamiprodjo M, Baumeister RG, Jakobs TF, Bauner KU, Boehm HF, Horng A, Reiser MF, Glaser C, Herrmann KA, Notohamiprodjo, Mike, Baumeister, Ruediger G H, Jakobs, Tobias F, Bauner, Kerstin U, Boehm, Holger F, Horng, Annie, Reiser, Maximilian F, Glaser, Christian, Herrmann, Karin A
Formato: research Journal Article
Publicado: Springer Nature Nov2009
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: MR-lymphangiography at 3.0 T--a feasibility study.
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          Notohamiprodjo M
          Baumeister RG
          Jakobs TF
          Bauner KU
          Boehm HF
          Horng A
          Reiser MF
          Glaser C
          Herrmann KA
          Notohamiprodjo, Mike
          Baumeister, Ruediger G H
          Jakobs, Tobias F
          Bauner, Kerstin U
          Boehm, Holger F
          Horng, Annie
          Reiser, Maximilian F
          Glaser, Christian
          Herrmann, Karin A
        affil: Department of Clinical Radiology, University-Hospitals Munich, Campus Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
      sug:
        subj:
          Lymphatic System Pathology
          Lymphedema Pathology
          Lymphocele Pathology
          Lymphography Methods
          Magnetic Resonance Imaging Methods
          Adult
          Contrast Media Pharmacodynamics
          Pilot Studies
          Female
          Human
          Lymph Nodes Pathology
          Lymphedema Diagnosis
          Lymphocele Diagnosis
          Male
          Middle Age
          Reproducibility of Results
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: The purpose of this study was to establish and evaluate contrast-enhanced MR-lymphangiography (MRL) at 3.0 T for detection and visualization of abnormalities of the peripheral lymphatic system. Sixteen patients were examined with a highly resolved isotropic T1w-3D-GRE-(FLASH) sequence (TR 3.76 ms/TE 1.45 ms/FA 30 degrees /voxel-size 0.8 x 0.8 x 0.8 mm(3)) at 3T after intracutaneous injection of gadolinium-diethylene-triamine-pentaacetic-acid. Two radiologists evaluated overall image quality, contrast between lymph vessels and background tissue, venous contamination, visualized levels, and fat-saturation-homogeneity on 3D maximum-intensity projections. Overall image quality was good to excellent, and all examinations were diagnostic except one, where contrast medium was injected subcutaneously instead of intracutaneously. Overall image quality was good to excellent in 12/16 cases, depiction of lymph vessels was good to excellent in 15/16 cases. Venous contamination was always present, but diagnostically problematical in only one case. Instant lymphatic drainage was observed in unaffected extremities, reaching the pelvic level after approximately 10 min. Lymphatic drainage was considerably delayed in lymphedematous extremities. Ectatic lymph vessels, entrapment, and diffuse drainage of contrast medium correlated with impaired lymphatic drainage. In conclusion, MRL at 3.0 T provides very high spatial resolution and anatomical detail of normal and abnormal peripheral lymph vessels. MRL may thus become a valuable tool for microsurgical treatment planning and monitoring.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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