Pitfalls in FMRI.
Several different techniques allow a functional assessment of neuronal activations by magnetic resonance imaging (fMRI). The by far most influential fMRI technique is based on a local T2*-sensitive hemodynamic response to neuronal activation, also known as the blood oxygenation level dependent or BO...
| Publicado en: | European Radiology Vol. 19; no. 11; pp. 2689 - 2707 |
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| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Nov2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105230775&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105230775 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Nov2009 vid: 19 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105230775 44645606 NLM19504107 2010440215 10.1007/s00330-009-1456-9 NLM19504107 105230775 ppf: 2689 ppct: 18 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Pitfalls in FMRI. aug: au: Haller S Bartsch AJ Haller, Sven Bartsch, Andreas J affil: Institute of Radiology, Department of Neuroradiology, University Hospital Basel, Petersgraben 4, CH 4031 Basel, Switzerland sug: subj: Magnetic Resonance Imaging Methods Neurons Pathology Oxygen Artifacts Brain Pathology Brain Mapping Methods Electroencephalography Methods False Positive Results Human Image Processing, Computer Assisted Methods Movement Factor Analysis Reproducibility of Results Time Factors ab: Several different techniques allow a functional assessment of neuronal activations by magnetic resonance imaging (fMRI). The by far most influential fMRI technique is based on a local T2*-sensitive hemodynamic response to neuronal activation, also known as the blood oxygenation level dependent or BOLD effect. Consequently, the term 'fMRI' is often used synonymously with BOLD imaging. Because interpretations of fMRI brain activation maps often appear intuitive and compelling, the reader might be tempted not to critically question the fundamental processes and assumptions. We review some essential processes and assumptions of BOLD fMRI and discuss related confounds and pitfalls in fMRI - from the underlying physiological effect, to data acquisition, data analysis and the interpretation of the results including clinical fMRI. A background framework is provided for the systematic and critical interpretation of fMRI results. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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