Clinical Doppler ultrasound for the assessment of plaque ulceration in the stenosed carotid bifurcation by detection of distal turbulence intensity: a matched model study.
The assessment of flow disturbances due to carotid plaque ulceration may provide added diagnostic information to Doppler ultrasound (DUS) of the carotid stenosis, and indicate whether the associated hemodynamics are a potential thromboembolic source. We evaluated the effect of ulceration in a modera...
| Publicado en: | European Radiology Vol. 19; no. 11; pp. 2739 - 2750 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Nov2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105230782&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105230782 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Nov2009 vid: 19 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105230782 44645612 NLM19547987 2010440222 10.1007/s00330-009-1457-8 NLM19547987 105230782 ppf: 2739 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Clinical Doppler ultrasound for the assessment of plaque ulceration in the stenosed carotid bifurcation by detection of distal turbulence intensity: a matched model study. aug: au: Wong EY Nikolov HN Thorne ML Poepping TL Rankin RN Holdsworth DW Wong, Emily Y Nikolov, Hristo N Thorne, Meghan L Poepping, Tamie L Rankin, Richard N Holdsworth, David W affil: Robarts Research Institute, University of Western Ontario, 100 Perth Drive, London, ON, Canada N6A5K8 sug: subj: Carotid Arteries Pathology Carotid Arteries Ultrasonography Carotid Stenosis Pathology Carotid Stenosis Therapy Carotid Stenosis Ultrasonography Ultrasonography, Doppler Methods Computer Simulation Constriction, Pathologic Hemodynamics Human Diagnostic Imaging Models, Biological Phantoms, Imaging Reproducibility of Results Thromboembolism Radiography Thromboembolism Therapy Thromboembolism Ultrasonography ab: The assessment of flow disturbances due to carotid plaque ulceration may provide added diagnostic information to Doppler ultrasound (DUS) of the carotid stenosis, and indicate whether the associated hemodynamics are a potential thromboembolic source. We evaluated the effect of ulceration in a moderately stenosed carotid bifurcation on distal turbulence intensity (TI) measured using clinical DUS in matched anthropomorphic models. Several physiologically relevant ulcer geometries (hemispherical, mushroom-shaped, and ellipsoidal pointing distally and proximally) and sizes (2-mm, 3-mm and 4-mm diameter hemispheres) were investigated. An offline analysis was performed to determine several velocity-based parameters from ensemble-averaged spectral data, including TI. Significant elevations in TI were observed in the post-stenotic flow field of the stenosed carotid bifurcation by the inclusion of ulceration (P < 0.001) in a region two common carotid artery diameters distal to the site of ulceration during the systolic peak and the diastolic phase of the cardiac cycle. Both the size and shape of ulceration had a significant effect on TI in the distal region (P < 0.001). Due to the use of a clinical system, this method provides the means to evaluate for plaque ulcerations in patients with carotid atherosclerosis using DUS. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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