ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: a comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays.

Purpose: Recently, several novel molecular prognostic markers were identified in cytogenetically normal acute myeloid leukemia (CN-AML). In addition to the well-known influence of FLT3, NPM1, and CEBPA mutations, high transcript levels of the ERG, BAALC, and MN1 genes have been associated with infer...

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Bibliographic Details
Published in:Journal of Clinical Oncology Vol. 27; no. 30; pp. 5031 - 5039
Main Authors: Metzeler KH, Dufour A, Benthaus T, Hummel M, Sauerland MC, Heinecke A, Berdel WE, Büchner T, Wörmann B, Mansmann U, Braess J, Spiekermann K, Hiddemann W, Buske C, Bohlander SK, Metzeler, Klaus H, Dufour, Annika, Benthaus, Tobias, Hummel, Manuela, Sauerland, Maria-Cristina
Format: research Journal Article
Published: American Society of Clinical Oncology 10/20/2009
Online Access:View this record in EBSCOhost