Population pharmacokinetics of recombinant factor VIII:C (ReFacto®) in adult HIV-negative and HIV-positive haemophilia patients.

PURPOSE: The aim of this study was to explore possible differences in the pharmacokinetics (PK) of recombinant factor VIII:C (ReFacto - ReFacto ) in HIV+ vs. HIV- patients and also differences in the chromogenic substrate bioassay (CHS) and one-stage clotting (OSC) methods. METHODS: Twenty-eight hae...

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Bibliographic Details

Published in:	European Journal of Clinical Pharmacology Vol. 65; no. 11; pp. 1121 - 1131
Main Authors:	Karafoulidou A, Suarez E, Anastasopoulou I, Katsarou O, Kouramba A, Kotsi P, Zografidis A, Lukas JC
Format:	research tables/charts Journal Article
Published:	Springer Nature Nov2009
Online Access:	View this record in EBSCOhost