Mucocutaneous manifestations in 150 HIV-infected Indian patients and their relationship with CD4 lymphocyte counts.

Mucocutaneous findings in 150 HIV+ve cases (F, 79; M, 71) were evaluated over a one-year period. Mucocutaneous manifestations were seen in 96% with 2.9 mean number of dermatoses and mean cluster of differentiation (CD4) count of 196.33 cells/mm(3). The highest number of mean dermatoses, 3.29, was se...

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Publicado en:International Journal of STD & AIDS Vol. 20; no. 11; pp. 771 - 775
Autores principales: Sud N, Shanker V, Sharma A, Sharma NL, Gupta M
Formato: Journal Article
Publicado: Sage Publications Inc. Nov2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2009
      vid: 20
      iid: 11
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        105235294
        2010455385
        10.1258/ijsa.2009.009092
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        atl: Mucocutaneous manifestations in 150 HIV-infected Indian patients and their relationship with CD4 lymphocyte counts.
      aug:
        au:
          Sud N
          Shanker V
          Sharma A
          Sharma NL
          Gupta M
        affil: Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College, Shimla, India.
      sug:
        subj:
          HIV Infections Complications
          HIV Infections Immunology
          Mouth Diseases Epidemiology
          Skin Diseases Epidemiology
          Adult
          Alopecia Epidemiology
          CD4 Lymphocyte Count
          Candidiasis Epidemiology
          Seborrhea Epidemiology
          Female
          Ichthyosis Epidemiology
          India
          Male
          Paronychia Epidemiology
          Periodontitis Epidemiology
          Pigmentation
          Prevalence
          Pyoderma Epidemiology
          Scabies Epidemiology
          Adult: 19-44 years
          Female
          Male
      ab: Mucocutaneous findings in 150 HIV+ve cases (F, 79; M, 71) were evaluated over a one-year period. Mucocutaneous manifestations were seen in 96% with 2.9 mean number of dermatoses and mean cluster of differentiation (CD4) count of 196.33 cells/mm(3). The highest number of mean dermatoses, 3.29, was seen in individuals with severe immunosuppression. The most common mucocutaneous manifestation seen was candidiasis (35.33%), followed by seborrhoeic dermatitis (31.33%), oral pigmentation (29.33%), xerosis/ichthyosis (22.67%), pyodermas (22%), periodontitis (17.33%) and nail pigmentation (16.67%). Patient stratification according to the WHO immunological staging, according to CD4 counts, showed a statistically significant association (P < 0.05) for candidiasis, scabies, paronychia, oral pigmentation and diffuse hair loss. Nail and oral pigmentary changes, trichomegaly and subcutaneous fungal infections caused by dermatophytes were highlights of the study. Incidences of xerosis/ichthyosis, pyodermas, scabies and molluscum contagiosum reported in our study were higher and pruritic popular eruptions was lower than those in previous Indian studies. Cutaneous neoplasms were not seen in the present study.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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