The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study.
Objective: This study evaluated the effect of a Computerized Physician Order Entry system with basic Clinical Decision Support (CPOE/CDSS) on the incidence of medication errors (MEs) and preventable adverse drug events (pADEs).Design: Interrupted time-series design.Measurements: The primary outcome...
| Publicado en: | Journal of the American Medical Informatics Association Vol. 16; no. 6; pp. 816 - 826 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
Nov/Dec2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105241414&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105241414 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10675027 FZ9 jtl: Journal of the American Medical Informatics Association issn: 10675027 maglogo: N pubinfo: dt: Nov/Dec2009 vid: 16 iid: 6 pid: 622 pub: Oxford University Press / USA artinfo: ui: 105241414 NLM19717798 2010467561 10.1197/jamia.M3099 NLM19717798 105241414 ppf: 816 ppct: 10 formats: tig: atl: The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study. aug: au: van Doormaal JE van den Bemt PM Zaal RJ Egberts AC Lenderink BW Kosterink JG Haaijer-Ruskamp FM Mol PG van Doormaal, Jasperien E van den Bemt, Patricia M L A Zaal, Rianne J Egberts, Antoine C G Lenderink, Bertil W Kosterink, Jos G W Haaijer-Ruskamp, Flora M Mol, Peter G M affil: Department of Hospital and Clinical Pharmacy, University Medical Center Groningen, P.O. Box 30,001, 9,700 RB Groningen, The Netherlands sug: subj: Medication Errors Prevention and Control Outcome Assessment Prescriptions, Drug Aged Female Human Linear Regression Male Middle Age Netherlands Prospective Studies Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objective: This study evaluated the effect of a Computerized Physician Order Entry system with basic Clinical Decision Support (CPOE/CDSS) on the incidence of medication errors (MEs) and preventable adverse drug events (pADEs).Design: Interrupted time-series design.Measurements: The primary outcome measurements comprised the percentage of medication orders with one or more MEs and the percentage of patients with one or more pADEs.Results: Pre-implementation, the mean percentage of medication orders containing at least one ME was 55%, whereas this became 17% post-implementation. The introduction of CPOE/CDSS has led to a significant immediate absolute reduction of 40.3% (95% CI: -45.13%; -35.48%) in medication orders with one or more errors. Pre-implementation, the mean percentage of admitted patients experiencing at least one pADE was 15.5%, as opposed to 7.3% post-implementation. However, this decrease could not be attributed to the introduction of CPOE/CDSS: taking into consideration the interrupted time-series design, the immediate change was not significant (-0.42%, 95% CI: -15.52%; 14.68%) because of the observed underlying negative trend during the pre-CPOE period of -4.04% [95% CI: -7.70%; -0.38%] per month.Conclusions: This study has shown that CPOE/CDSS reduces the incidence of medication errors. However, a direct effect on actual patient harm (pADEs) was not demonstrated. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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