Muscle functional magnetic resonance imaging and acute low back pain: a pilot study to characterize lumbar muscle activity asymmetries and examine the effects of osteopathic manipulative treatment.

BACKGROUND: Muscle functional magnetic resonance imaging (mfMRI) measures transverse relaxation time (T2), and allows for determination of the spatial pattern of muscle activation. The purposes of this pilot study were to examine whether MRI-derived T2 or side-to-side differences in T2 (asymmetries)...

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Publicado en:Osteopathic Medicine & Primary Care Vol. 3; pp. 10p - 11
Autores principales: Clark BC, Walkowski S, Conatser RR, Eland DC, Howell JN
Formato: diagnostic images research tables/charts Journal Article
Publicado: BioMed Central 2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2009
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      pub: BioMed Central
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        10.1186/1750-4732-3-7
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        atl: Muscle functional magnetic resonance imaging and acute low back pain: a pilot study to characterize lumbar muscle activity asymmetries and examine the effects of osteopathic manipulative treatment.
      aug:
        au:
          Clark BC
          Walkowski S
          Conatser RR
          Eland DC
          Howell JN
        affil: Institute for Neuromusculoskeletal Research, Ohio University College of Osteopathic Medicine, Northfield, OH, USA; clarkb2@ohio.edu.
      sug:
        subj:
          Low Back Pain Prevention and Control
          Manipulation, Osteopathic
          Muscle, Skeletal Radiography
          Adult
          Aged
          Body Weights and Measures
          Clinical Assessment Tools
          Data Analysis Software
          Descriptive Statistics
          Erector Spinae Muscles
          Female
          Funding Source
          Magnetic Resonance Imaging
          Male
          Middle Age
          Multifidus Muscles
          One-Way Analysis of Variance
          Pearson's Correlation Coefficient
          Physical Examination
          Pilot Studies
          Post Hoc Analysis
          Psoas Muscles
          Repeated Measures
          Software
          Time Factors
          Visual Analog Scaling
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: BACKGROUND: Muscle functional magnetic resonance imaging (mfMRI) measures transverse relaxation time (T2), and allows for determination of the spatial pattern of muscle activation. The purposes of this pilot study were to examine whether MRI-derived T2 or side-to-side differences in T2 (asymmetries) differ in low back muscles between subjects with acute low back pain (LBP) compared to asymptomatic controls, and to determine if a single osteopathic manipulative treatment (OMT) session alters these T2 properties immediately and 48-hours after treatment. METHODS: Subjects with non-specific acute LBP (mean score on 110 visual analog score = 3.02 +/- 2.81) and asymptomatic controls (n = 9/group) underwent an MRI, and subsequently the LBP subjects received OMT and then underwent another MRI. The LBP subjects reported back for an additional MRI 48-hours following their initial visit. T2 and T2 asymmetry were calculated from regions of interest for the psoas, quadratus lumborum (QL), multifidus, and iliocostalis lumborum/longissimus thoracis (IL/LT) muscles. RESULTS: No differences were observed between the groups when T2 was averaged for the left and right side muscles. However, the QL displayed a significantly greater T2 asymmetry in LBP subjects when compared to controls (29.1 +/- 4.3 vs. 15.9 +/- 4.1%; p = 0.05). The psoas muscle also displayed a relatively large, albeit non-significant, mean difference (22.7 +/- 6.9 vs. 9.5 +/- 2.8%; p = 0.11). In the subjects with LBP, psoas T2 asymmetry was significantly reduced immediately following OMT (25.3 +/- 6.9 to 6.1 +/- 1.8%, p = 0.05), and the change in LBP immediately following OMT was correlated with the change in psoas T2 asymmetry (r = 0.75, p = 0.02). CONCLUSION: Collectively, this pilot work demonstrates the feasibility of mfMRI for quantification and localization of muscle abnormalities in patients with acute low back pain. Additionally, this pilot work provides insight into the mechanistic actions of OMT during acute LBP, as it suggests that it may attenuate muscle activity asymmetries of some of the intrinsic low back muscles.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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