Intra- and interhemispheric variations of diffusivity in subcortical white matter in normal human brain.
Our purpose was to reveal potential regional variations in water molecular diffusivity within each cerebral hemisphere and across the right and left hemispheres. Diffusion-weighted images of 44 healthy right-handed adult male subjects were obtained using a diffusion tensor imaging sequence. Mean dif...
| Publicado en: | European Radiology Vol. 20; no. 1; pp. 227 - 234 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jan2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105285609&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105285609 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jan2010 vid: 20 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105285609 47410925 NLM19657648 2010528184 10.1007/s00330-009-1534-z NLM19657648 105285609 ppf: 227 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Intra- and interhemispheric variations of diffusivity in subcortical white matter in normal human brain. aug: au: Yoshiura T Noguchi T Hiwatashi A Togao O Yamashita K Nagao E Kamano H Honda H Yoshiura, Takashi Noguchi, Tomoyuki Hiwatashi, Akio Togao, Osamu Yamashita, Koji Nagao, Eiki Kamano, Hironori Honda, Hiroshi affil: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan sug: subj: Body Water Metabolism Brain Anatomy and Histology Brain Metabolism Magnetic Resonance Imaging Methods Nerve Fibers Metabolism Water Metabolism Adult Diffusion Human Image Interpretation, Computer Assisted Methods Male Middle Age Nerve Fibers Reference Values Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Middle Aged: 45-64 years Male ab: Our purpose was to reveal potential regional variations in water molecular diffusivity within each cerebral hemisphere and across the right and left hemispheres. Diffusion-weighted images of 44 healthy right-handed adult male subjects were obtained using a diffusion tensor imaging sequence. Mean diffusivity (MD) values in subcortical white matter (WM) within 39 regions in each hemisphere were measured using an automated method. Intrahemispheric comparisons of MDs in subcortical WM were performed among six brain regions (frontal, parietal, occipital and temporal lobes and pre- and postcentral gyri). Interhemispheric comparisons of MDs were performed between the right and left counterparts of the 39 regions. In both hemispheres, diffusivity in the precentral gyrus was lower than those in other regions, while diffusivity in the parietal lobe was higher than others. MD asymmetry in which the left was lower than the right was found in the parietal lobe, middle occipital gyrus, and medial and orbital aspects of the frontal lobe. The converse asymmetry was revealed in the frontal operculum, supplementary motor cortex, temporal lobe, limbic cortices, precuneus and cuneus. Our results revealed significant intra- and interhemispheric regional variations in MD in subcortical WM, which may be related to different densities of axons and myelin sheaths. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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