Do nutritional markers in wound fluid reflect pressure ulcer status?
Evaluation of wound fluid characteristics for pressure ulcer (PU) assessment in clinical settings remains subjective, requiring considerable expertise. This crosssectional study focused on nutritional markers in wound fluid as possible objective tools and investigated whether they reflect the PU sta...
| Publicado en: | Wound Repair & Regeneration Vol. 18; no. 1; pp. 31 - 38 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jan/Feb2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105286579&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105286579 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10671927 DPV jtl: Wound Repair & Regeneration issn: 10671927 maglogo: Y pubinfo: dt: Jan/Feb2010 vid: 18 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 105286579 2010529222 10.1111/j.1524-475X.2009.00564.x 105286579 ppf: 31 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Do nutritional markers in wound fluid reflect pressure ulcer status? aug: au: Iizaka S Sanada H Minematsu T Oba M Nakagami G Koyanagi H Nagase T Konya C Sugama J affil: Department of Gerontological Nursing/Wound Care Management, Faculty of Medicine Bldg. No.5-308, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; iizaka-tky@umin.ac.jp sug: subj: Biological Markers Nutrition Pressure Ulcer Diagnosis Aged Aged, 80 and Over Amino Acids Analysis Blood Glucose Blood Blood Urea Nitrogen C-Reactive Protein Blood Clinical Assessment Tools Comorbidity Creatine Blood Cross Sectional Studies Data Analysis Software Female Funding Source Glucose Analysis Human Male Mann-Whitney U Test Middle Age Nonexperimental Studies Pressure Ulcer Epidemiology Pressure Ulcer Physiopathology Prevalence Proteins Blood Scales Spearman's Rank Correlation Coefficient Wound Healing Physiology Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: Evaluation of wound fluid characteristics for pressure ulcer (PU) assessment in clinical settings remains subjective, requiring considerable expertise. This crosssectional study focused on nutritional markers in wound fluid as possible objective tools and investigated whether they reflect the PU status according to the healing phase, infection, and granulation, especially after adjusting for serum values. Twenty-eight patients with 32 full-thickness PUs were studied. The concentration of albumin, total protein, glucose, and zinc in wound fluid were measured. For PU status, the healing phases and infection were evaluated by clinical signs, and the degree of granulation tissue formation was determined as the hydroxyproline concentration. The wound fluid/serum ratio for albumin was significantly lower during the inflammatory phase than during the proliferative phase (p=0.020). Infected wound fluid contained less glucose (0.3-1.0 mmol/L) than noninfected ones did (5.0-7.6 mmol/L) in an intraindividual comparison of three cases. The wound fluid/serum ratio for glucose was negatively correlated with hydroxyproline level in the proliferative phase (þ=-0.73, p=0.007), while zinc level in wound fluid showed a positive correlation (þ=0.61, p=0.028). Our results suggest that these traditional nutritional markers in wound fluid, especially wound fluid/serum ratio may be useful to evaluate local PU status. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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