Upper limb function and brain reorganization after constraint-induced movement therapy in children with hemiplegia.

Objective: The aims of this study were to (1) investigate the effectiveness of CIMT for children with hemiplegia, (2) determine the feasibility of using fMRI for describing brain activity patterns before and after CIMT and (3) describe changes in brain reorganization after CIMT in children with hemi...

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Publicado en:Developmental Neurorehabilitation Vol. 13; no. 1; pp. 19 - 31
Autores principales: Cope SM, Liu X, Verber MD, Cayo C, Rao S, Tassone JC
Formato: diagnostic images research tables/charts tracings Journal Article
Publicado: Taylor & Francis Ltd Feb2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2010
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      pub: Taylor & Francis Ltd
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        atl: Upper limb function and brain reorganization after constraint-induced movement therapy in children with hemiplegia.
      aug:
        au:
          Cope SM
          Liu X
          Verber MD
          Cayo C
          Rao S
          Tassone JC
        affil: Concordia University Wisconsin, Rehabilitation Science, Mequon USA
      sug:
        subj:
          Brain Physiology
          Constraint-Induced Therapy
          Hemiplegia Rehabilitation
          Upper Extremity Physiology
          Adolescence
          Child
          Clinical Assessment Tools
          Convenience Sample
          Descriptive Statistics
          Female
          Funding Source
          Human
          Magnetic Resonance Imaging
          Male
          Multiple Regression
          Pretest-Posttest Design
          Questionnaires
          Treatment Outcomes
          Videorecording
          Wilcoxon Rank Sum Test
          Wisconsin
          Adolescent: 13-18 years
          Child: 6-12 years
          Female
          Male
      ab: Objective: The aims of this study were to (1) investigate the effectiveness of CIMT for children with hemiplegia, (2) determine the feasibility of using fMRI for describing brain activity patterns before and after CIMT and (3) describe changes in brain reorganization after CIMT in children with hemiplegia using fMRI. Design: Before and after study with one group. Methods: Ten children aged 7-14 years ( M = 11.0, SD = 2.5) with hemiplegia received CIMT over a 2-week period using a before and after design. Clinical measures included the Melbourne Assessment of Unilateral Upper Limb Function, upper limb kinematics and parent questionnaire. Children were measured with fMRI before and after CIMT. Results: Findings showed that CIMT may be effective at improving upper limb function in some, but not all children; those children with a moderate degree of impairment seemed to benefit the most. fMRI findings correlated moderately with clinical measures. Conclusion: Although unique challenges with fMRI data collection exist for this population, it provides potentially valuable information to better understand mechanisms of change after interventions such as CIMT.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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