The effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of glipizide in Chinese subjects.

To study the effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of glipizide. Eighteen healthy male subjects were divided into three groups according to their genotypes: group I, CYP2C9*1/*1 and CYP2C19 extensive metabolizers (EMs); group II, CYP2C9*1/*1...

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Detalles Bibliográficos
Publicado en:European Journal of Clinical Pharmacology Vol. 66; no. 2; pp. 145 - 152
Autores principales: Tan B, Zhang Y, Chen X, Zhao X, Li G, Zhong D
Formato: research tables/charts Journal Article
Publicado: Springer Nature Feb2010
Acceso en línea:Ver este registro en EBSCOhost