Diffusion imaging and tractography of congenital brain malformations.
Diffusion imaging is an MRI modality that measures the microscopic molecular motion of water in order to investigate white matter microstructure. The modality has been used extensively in recent years to investigate the neuroanatomical basis of congenital brain malformations. We review the basic pri...
| Publicado en: | Pediatric Radiology Vol. 40; no. 1; pp. 59 - 68 |
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| Autores principales: | , , , , , |
| Formato: | review Journal Article |
| Publicado: |
Springer Nature
Jan2010
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105294718&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105294718 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03010449 O03 jtl: Pediatric Radiology issn: 03010449 maglogo: N pubinfo: dt: Jan2010 vid: 40 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105294718 105294718 NLM19937239 2010538128 10.1007/s00247-009-1448-6 NLM19937239 105294718 ppf: 59 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Diffusion imaging and tractography of congenital brain malformations. aug: au: Wahl M Barkovich AJ Mukherjee P Wahl, Michael Barkovich, A James Mukherjee, Pratik affil: Department of Neurology, University of California, San Francisco, San Francisco, CA 94143-0628, USA sug: subj: Brain Abnormalities Brain Pathology Brain Diseases Brain Diseases Diagnosis Magnetic Resonance Imaging Methods Nerve Fibers Pathology Child Child: 6-12 years ab: Diffusion imaging is an MRI modality that measures the microscopic molecular motion of water in order to investigate white matter microstructure. The modality has been used extensively in recent years to investigate the neuroanatomical basis of congenital brain malformations. We review the basic principles of diffusion imaging and of specific techniques, including diffusion tensor imaging (DTI) and high angular resolution diffusion imaging (HARDI). We show how DTI and HARDI, and their application to fiber tractography, has elucidated the aberrant connectivity underlying a number of congenital brain malformations. Finally, we discuss potential uses for diffusion imaging of developmental disorders in the clinical and research realms. pubtype: Academic Journal doctype: review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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