True detection versus 'accidental' detection of small lung cancer by a computer-aided detection (CAD) program on chest radiographs.

To evaluate the number of actual detections versus 'accidental' detections by a computer-aided detection (CAD) system for small nodular lung cancers (<=30 mm) on chest radiographs, using two different criteria for measuring performance. A Food-and-Drug-Administration-approved CAD program (version 1....

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Publicado en:Journal of Digital Imaging Vol. 23; no. 1; pp. 66 - 73
Autores principales: Li F, Engelmann R, Doi K, MacMahon H
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Feb2010
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2010
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      pub: Springer Nature
      place: New York, New York
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        atl: True detection versus 'accidental' detection of small lung cancer by a computer-aided detection (CAD) program on chest radiographs.
      aug:
        au:
          Li F
          Engelmann R
          Doi K
          MacMahon H
        affil: Kurt Rossmann Laboratories for Radiologic Image Research, Department of Radiology, MC2026, The University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637
      sug:
        subj:
          Diagnosis, Computer Assisted
          Lung Neoplasms Diagnosis
          Adult
          Aged
          Aged, 80 and Over
          Chi Square Test
          Comparative Studies
          Diagnostic Errors
          Evaluation Research
          False Positive Results
          Female
          Human
          Male
          Middle Age
          Radiography, Thoracic
          Sensitivity and Specificity
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: To evaluate the number of actual detections versus 'accidental' detections by a computer-aided detection (CAD) system for small nodular lung cancers (<=30 mm) on chest radiographs, using two different criteria for measuring performance. A Food-and-Drug-Administration-approved CAD program (version 1.0; Riverain Medical) was applied to 34 chest radiographs with a 'radiologist-missed' nodular cancer and 36 radiographs with a radiologist-mentioned nodule (a newer version 3.0 was also applied to the 36-case database). The marks applied by this CAD system consisted of 5-cm-diameter circles. A strict 'nodule-in-center' criterion and a generous 'nodule-in-circle' criterion were compared as methods for the calculation of CAD sensitivity. The increased sensitivities by the nodule-in-circle criterion were considered as nodules detected by chance. The number of false-positive (FP) marks was also analyzed. For the 34 radiologist-missed cancers, the nodule-in-circle criterion caused eight more cancers (24%) to be detected by chance, as compared to the nodule-in-center criterion, when using the version 1.0 results. For the 36 radiologist-mentioned nodules, the nodule-in-circle criterion caused seven more lesions (19%) to be detected by chance, as compared to the nodule-in-center criterion, when using the version 1.0 results, and three more lesions (8%) to be detected by chance when using the version 3.0 results. Version 1.0 yielded a mean of six FP marks per image, while version 3.0 yielded only three FP marks per image. The specific criteria used to define true- and false-positive CAD detections can substantially influence the apparent accuracy of a CAD system.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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