Patient attitudinal and behavioral factors associated with warfarin non-adherence at outpatient anticoagulation clinics.
BACKGROUND: Warfarin is an anticoagulant effective in preventing stroke, but it has a narrow therapeutic range requiring optimal adherence to achieve the most favorable effects. PURPOSE: The goal of this study was to examine specific patient factors that might help explain warfarin non-adherence at...
| Publicado en: | International Journal of Behavioral Medicine Vol. 17; no. 1; pp. 33 - 43 |
|---|---|
| Autores principales: | , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Mar2010
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105305902&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105305902 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10705503 7M2 jtl: International Journal of Behavioral Medicine issn: 10705503 maglogo: N pubinfo: dt: Mar2010 vid: 17 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105305902 2010551379 10.1007/s12529-009-9052-6 NLM19579066 105305902 ppf: 33 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Patient attitudinal and behavioral factors associated with warfarin non-adherence at outpatient anticoagulation clinics. aug: au: Cruess D Localio A Platt A Brensinger C Christie J Gross R Parker C Price M Metlay J Cohen A Newcomb C Strom B Kimmel S affil: Department of Psychology, University of Connecticut, 406 Babbidge Road, Unit 1020 Storrs 06269-1020 USA sug: subj: Ambulatory Care Medication Compliance Patient Attitudes Warfarin Therapeutic Use Adult Clinical Assessment Tools Confidence Intervals Descriptive Statistics Drug Administration Methods Female Funding Source Human Logistic Regression Male Middle Age Odds Ratio P-Value Pearson's Correlation Coefficient Self Report Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: BACKGROUND: Warfarin is an anticoagulant effective in preventing stroke, but it has a narrow therapeutic range requiring optimal adherence to achieve the most favorable effects. PURPOSE: The goal of this study was to examine specific patient factors that might help explain warfarin non-adherence at outpatient anticoagulation clinics. METHOD: In a prospective cohort study of 156 adults, we utilized logistic regression analyses to examine the relationship between the five Treatment Prognostics scales from the Millon Behavioral Medicine Diagnostic (MBMD), as well as three additional MBMD scales (Depression, Future Pessimism, and Social Isolation), and daily warfarin non-adherence assessed using electronic medication event monitoring systems caps over a median of 139 days. RESULTS: Four of the five Treatment Prognostic scales and greater social isolation were associated with warfarin non-adherence. When controlling for pertinent demographic and medical variables, the Information Discomfort scale remained significantly associated with warfarin non-adherence over time. CONCLUSION: Although several factors were related to warfarin non-adherence, patients reporting a lack of receptivity to details regarding their medical illness seemed most at risk for warfarin non-adherence. This information might aid in the development of interventions to enhance warfarin adherence and perhaps reduce adverse medical events. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|