Computational model of steroidogenesis in human H295R cells to predict biochemical response to endocrine-active chemicals: model development for metyrapone [corrected] [published erratum appears in ENVIRON HEALTH PERSPECT 2011 Jan;119(1):A11].

Background: An in vitro steroidogenesis assay using the human adrenocortical carcinoma cell line H295R is being evaluated as a possible screening assay to detect and assess the impact of endocrineactive chemicals (EACs) capable of altering steroid biosynthesis. Data interpretation and their quantita...

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Detalles Bibliográficos
Publicado en:Environmental Health Perspectives Vol. 118; no. 2; pp. 265 - 273
Autores principales: Breen MS, Breen M, Terasaki N, Yamazaki M, Conolly RB
Formato: equations & formulas research tables/charts Journal Article
Publicado: National Institute of Environmental Health Sciences Feb2010
Acceso en línea:Ver este registro en EBSCOhost