Comparison of three different iodine-based bowel regimens for CT colonography.

Objective: The aim of this study was to compare the computed tomographic colonography (CTC) image quality and patient acceptance of three iodine-based faecal tagging bowel preparations in 60 patients undergoing the following regimens: a 2-day regimen of meal-time administration of iodine and phospho...

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Publicado en:European Radiology Vol. 20; no. 2; pp. 348 - 359
Autores principales: Campanella D, Morra L, Delsanto S, Tartaglia V, Asnaghi R, Bert A, Neri E, Regge D, Campanella, Delia, Morra, Lia, Delsanto, Silvia, Tartaglia, Vincenzo, Asnaghi, Roberto, Bert, Alberto, Neri, Emanuele, Regge, Daniele
Formato: research Journal Article
Publicado: Springer Nature Feb2010
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Comparison of three different iodine-based bowel regimens for CT colonography.
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          Campanella D
          Morra L
          Delsanto S
          Tartaglia V
          Asnaghi R
          Bert A
          Neri E
          Regge D
          Campanella, Delia
          Morra, Lia
          Delsanto, Silvia
          Tartaglia, Vincenzo
          Asnaghi, Roberto
          Bert, Alberto
          Neri, Emanuele
          Regge, Daniele
        affil: Radiology Unit, Institute for Cancer Research and Treatment, Strada Provinciale 142, Km 3,95, 10060 Candiolo, Italy
      sug:
        subj:
          Attitude to Health
          Colonography, Computed Tomographic Methods
          Colorectal Neoplasms Radiography
          Intestines Radiography
          Iodine Administration and Dosage
          Iodine Diagnostic Use
          Patient Attitudes
          Adult
          Aged
          Aged, 80 and Over
          Contrast Media
          Drug Administration Schedule
          Female
          Human
          Male
          Middle Age
          Reproducibility of Results
          Sensitivity and Specificity
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: The aim of this study was to compare the computed tomographic colonography (CTC) image quality and patient acceptance of three iodine-based faecal tagging bowel preparations in 60 patients undergoing the following regimens: a 2-day regimen of meal-time administration of iodine and phospho-soda (GFPH); a 2-day regimen of meal-time mild laxative, followed by iodine administered 2 h before CTC (SD); and a 2-day regimen of meal-time administration of iodine (GF).Methods: Two independent radiologists assessed tagging quality; quantitative measures included the tagged stool density, and computer-aided detection (CAD) false-positive rate.Results: The GFPH and SD regimens provided better subjective quality than GF (p < 0.001). The latter regimen resulted in a higher proportion of insufficiently tagged segments: the measured average stool density was less than 200 HU in 10.7% in all segments vs 3.6% for SD and <0.5% for GFPH, respectively. Insufficient tagging occurred mostly in the ascending colon and the caecum. The CAD false-positive rate increased following the trend: GFPH < SD < GF (p = 0.00012). GFPH was worse tolerated than SD (p < 0.05).Conclusions: Considering preparation quality alone, GFPH was the best regimen, but SD provided the best balance between bowel preparation quality and patient acceptability.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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