Ultrasound accelerates healing of normal wounds but not of ischemic ones.
To examine the influence of therapeutic ultrasound (US) on repair of standard and ischemic cutaneous lesions, full-thickness excisional wounds were made in rats and treated with a US 3 MHz, 0.5 W/cm2 pulsed duty cycle. We used five experimental groups: control (received US powered off on the day of...
| Published in: | Wound Repair & Regeneration Vol. 17; no. 6; pp. 825 - 832 |
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| Main Authors: | , , , , |
| Format: | pictorial research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
Nov/Dec2009
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105337195&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105337195 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10671927 DPV jtl: Wound Repair & Regeneration issn: 10671927 maglogo: Y pubinfo: dt: Nov/Dec2009 vid: 17 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 105337195 105337195 2010458067 10.1111/j.1524-475x.2009.00542.x 105337195 ppf: 825 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Ultrasound accelerates healing of normal wounds but not of ischemic ones. aug: au: Altomare M Nascimento AP Romana-Souza B Amadeu TP Monte-Alto-Costa A affil: Histology and Embryology Department, State University of Rio de Janeiro, Rio de Janeiro, Brazil sug: subj: Ischemia Complications Ultrasonography Methods Wound Care Methods Wound Healing Physiology Animal Studies Descriptive Statistics Immunohistochemistry Models, Biological Rats ab: To examine the influence of therapeutic ultrasound (US) on repair of standard and ischemic cutaneous lesions, full-thickness excisional wounds were made in rats and treated with a US 3 MHz, 0.5 W/cm2 pulsed duty cycle. We used five experimental groups: control (received US powered off on the day of surgery, and on the second and fourth day), control US (received US on the day of surgery, and on the second and fourth day), ischemic (received US powered off on the day of surgery, and on the second and fourth day), ischemic US 3X (received US on the day of surgery, and on the second and fourth day) and ischemic US 5X (received US in the day of surgery, first, second, third and fourth day). The control US group showed acceleration in wound contraction 7 days after wounding, an increase in collagen density, and only focal inflammatory areas. Neo-epidermis formation was more advanced in the control US group than in the control one. Wound contraction was delayed in the ischemic group when compared with the control group as well as the ischemic US 3X group, was but slightly accelerated in the ischemic US 5X group when compared with the ischemic group 7 days after wounding. Reepithelialization was delayed in both ischemic US groups when compared with the ischemic group. The number of inflammatory cells was higher in both US ischemic groups. We conclude that US therapy accelerates wound healing in normal wounds and delays wound healing in ischemic wounds. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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