Tracheobronchial pulmonary disease associated with pyoderma gangrenosum.

We report a tracheobronchial pulmonary manifestation caused by pyoderma gangrenosum, a neutrophilic dermatosis of unknown etiology. A 54-year-old man presented with pulmonary infiltrates followed by multiple painful cutaneous pustules on the scrotum. Skin biopsy showed pronounced neutrophilic infilt...

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Publicado en:Mayo Clinic Proceedings Vol. 84; no. 6; pp. 555 - 558
Autores principales: Kanoh S, Kobayashi H, Sato K, Motoyoshi K, Aida S, Kanoh, Soichiro, Kobayashi, Hideo, Sato, Ken, Motoyoshi, Kazuo, Aida, Shinsuke
Formato: case study Journal Article
Publicado: Elsevier B.V. Jun2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2009
      vid: 84
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      pub: Elsevier B.V.
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        10.1016/S0025-6196(11)60588-0
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        atl: Tracheobronchial pulmonary disease associated with pyoderma gangrenosum.
      aug:
        au:
          Kanoh S
          Kobayashi H
          Sato K
          Motoyoshi K
          Aida S
          Kanoh, Soichiro
          Kobayashi, Hideo
          Sato, Ken
          Motoyoshi, Kazuo
          Aida, Shinsuke
        affil: Division of Respiratory Medicine, Department of Medicine, National Defense Medical College, Saitama, Japan
      sug:
        subj:
          Lung Diseases Complications
          Pyoderma Gangrenosum Complications
          Bronchoscopy
          Lung Diseases Diagnosis
          Lung Diseases Pathology
          Male
          Middle Age
          Pyoderma Gangrenosum Diagnosis
          Pyoderma Gangrenosum Pathology
          Scrotum Pathology
          Middle Aged: 45-64 years
          Male
      ab: We report a tracheobronchial pulmonary manifestation caused by pyoderma gangrenosum, a neutrophilic dermatosis of unknown etiology. A 54-year-old man presented with pulmonary infiltrates followed by multiple painful cutaneous pustules on the scrotum. Skin biopsy showed pronounced neutrophilic infiltration without microorganism or granuloma, consistent with pyoderma gangrenosum. Bronchoscopy revealed multiple scattered polypoid nodules with a yellowish irregular surface from the trachea to bilateral bronchi; the appearance closely mimicked that of a skin lesion. Endobronchial biopsy demonstrated inflamed granulation and necrosis with infiltration by numerous neutrophils without vasculitis or granulomas, interpreted as pyoderma gangrenosum of the bronchi. Although the etiology of pyoderma gangrenosum is poorly understood, this case suggests that a common pathogenesis may account for the simultaneous cutaneous and airway inflammation.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
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