Computer-aided detection for the identification of pulmonary nodules in pediatric oncology patients: initial experience.

Background: Computer-aided detection (CAD) has been shown to increase the sensitivity for detection of pulmonary nodules in adults. This study reports initial findings utilizing a CAD system for the detection of pediatric pulmonary nodules.Objective: To assess the performance of CAD and pediatric ra...

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Publicado en:Pediatric Radiology Vol. 39; no. 7; pp. 685 - 694
Autores principales: Helm EJ, Silva CT, Roberts HC, Manson D, Seed MT, Amaral JG, Babyn PS, Helm, Emma J, Silva, Cicero T, Roberts, Heidi C, Manson, David, Seed, Mike T M, Amaral, Joao G, Babyn, Paul S
Formato: research Journal Article
Publicado: Springer Nature Jul2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2009
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      pub: Springer Nature
      place: New York, New York
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        atl: Computer-aided detection for the identification of pulmonary nodules in pediatric oncology patients: initial experience.
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          Helm EJ
          Silva CT
          Roberts HC
          Manson D
          Seed MT
          Amaral JG
          Babyn PS
          Helm, Emma J
          Silva, Cicero T
          Roberts, Heidi C
          Manson, David
          Seed, Mike T M
          Amaral, Joao G
          Babyn, Paul S
        affil: Department of Radiology, Churchill Hospital, Old Rd., Headington, Oxford, OX3 7LJ, UK
      sug:
        subj:
          Algorithms
          Artificial Intelligence
          Information Science Methods
          Radiographic Image Interpretation, Computer-Assisted Methods
          Tomography, X-Ray Computed Methods
          Adolescence
          Child
          Child, Preschool
          Female
          Lung Neoplasms
          Male
          Observer Bias
          Pilot Studies
          Radiographic Image Enhancement Methods
          Reproducibility of Results
          Sensitivity and Specificity
          Human
          Adolescent: 13-18 years
          Child: 6-12 years
          Child, Preschool: 2-5 years
          Female
          Male
      ab: Background: Computer-aided detection (CAD) has been shown to increase the sensitivity for detection of pulmonary nodules in adults. This study reports initial findings utilizing a CAD system for the detection of pediatric pulmonary nodules.Objective: To assess the performance of CAD and pediatric radiologists in the detection of pediatric pulmonary nodules.Materials and Methods: CT scans from a series of pediatric patients with known primary tumors and lung nodules were analyzed by four radiologists and a commercially available CAD system. IRB approval was obtained. Sensitivities were calculated for detection according to nodule size and location.Results: In 24 children (age 3-18 years) 173 nodules were identified. Overall the sensitivity of CAD was 34%, but the sensitivity of CAD for detection of nodules 4.0 mm or larger was 80%. Overall radiologist sensitivity ranged from 68% to 79%. There were 0.9 CAD false-positives and 0.3-2.4 radiologist false-positives per study.Conclusion: CAD in our pediatric oncology patients had good sensitivity for detection of lung nodules 4 mm and larger with a low number of false-positives. However, the sensitivity was considerably less for nodules smaller than 4 mm.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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