Influence of pharmacogenetics on indinavir disposition and short-term response in HIV patients initiating HAART.

AIMS: To assess the relationship between genetic polymorphisms and indinavir pharmacokinetic variability and to study the link between concentrations and short-term response or metabolic safety. METHODS: Forty protease inhibitor-naive patients initiating highly active antiretroviral therapy (HAART)...

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Bibliographic Details
Published in:European Journal of Clinical Pharmacology Vol. 65; no. 7; pp. 667 - 679
Main Authors: Bertrand J, Treluyer J, Panhard X, Tran A, Auleley S, Rey E, Salmon-Céron D, Duval X, Mentré F
Format: equations & formulas research tables/charts Journal Article
Published: Springer Nature Jul2009
Online Access:View this record in EBSCOhost