C-reactive protein: a useful marker for guiding duration of antibiotic therapy in suspected neonatal septicaemia?
The study aimed to determine whether serum C-reactive protein (CRP) levels can be used to identify when antibiotics can safely be discontinued in cases of suspected neonatal septicaemia. Neonates with suspected neonatal septicaemia treated at a hospital in Al Ramadi city, Iraq, in 2005 had serum CRP...
| Publicado en: | Eastern Mediterranean Health Journal Vol. 15; no. 2; pp. 269 - 276 |
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| Autor principal: | |
| Formato: | research tables/charts Journal Article |
| Publicado: |
World Health Organization
mar/abr2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105364251&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105364251 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10203397 Z0U jtl: Eastern Mediterranean Health Journal issn: 10203397 maglogo: N pubinfo: dt: mar/abr2009 vid: 15 iid: 2 pid: 437 pub: World Health Organization artinfo: ui: 105364251 43476817 2010322630 10.26719/2009.15.2.269 NLM19554972 105364251 ppf: 269 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: C-reactive protein: a useful marker for guiding duration of antibiotic therapy in suspected neonatal septicaemia? aug: au: Al-Zwaini EJ affil: Department of Paediatrics, College of Medicine, Al-Kindi Medical College, Baghdad University Baghdad, Iraq. ejkzwaini@yahoo.com sug: subj: Biological Markers C-Reactive Protein Blood Sepsis In Infancy and Childhood Treatment Duration Hematologic Tests Infant, Newborn Iraq Microbial Culture and Sensitivity Tests Nonexperimental Studies Prospective Studies Sensitivity and Specificity Human Infant, Newborn: birth-1 month ab: The study aimed to determine whether serum C-reactive protein (CRP) levels can be used to identify when antibiotics can safely be discontinued in cases of suspected neonatal septicaemia. Neonates with suspected neonatal septicaemia treated at a hospital in Al Ramadi city, Iraq, in 2005 had serum CRP and blood cultures (the gold standard) done at admission and at 48 hours, 4 days and 6 days after starting treatment. Of the 55 neonates, CRP was < or =6 mg/L at 48 hours in 37 (67.3%) and antibiotics could be stopped in 32 (82.5%), i.e., when blood culture was negative. The moderate sensitivity (78%) and negative predictive value (86%) of serum CRP in this study suggest that this test alone cannot be used for guiding duration of antibiotic treatment for neonatal sepsis. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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