How to combine ultrasound and cytological information in decision making about thyroid nodules.
The purpose of this study was to evaluate the role of sonographic-cytological correlation in determining which nodules should be reaspirated to reduce the false-negative rate of fine-needle aspiration biopsy (FNAB). A retrospective cohort study was performed on a database of 568 patients with 672 fo...
| Publicado en: | European Radiology Vol. 19; no. 8; pp. 1923 - 1932 |
|---|---|
| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Aug2009
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105373543&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105373543 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Aug2009 vid: 19 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105373543 42871656 NLM19277669 2010332407 10.1007/s00330-009-1369-7 NLM19277669 105373543 ppf: 1923 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: How to combine ultrasound and cytological information in decision making about thyroid nodules. aug: au: Kwak JY Kim EK Kim HJ Kim MJ Son EJ Moon HJ Kwak, Jin Young Kim, Eun-Kyung Kim, Hye Jung Kim, Min Jung Son, Eun Ju Moon, Hee Jung affil: Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea sug: subj: Biopsy, Needle Statistics and Numerical Data Image Enhancement Methods Image Interpretation, Computer Assisted Methods Thyroid Neoplasms Diagnosis Thyroid Neoplasms Epidemiology Ultrasonography Statistics and Numerical Data Adolescence Adult Aged False Negative Results Female South Korea Male Middle Age Prevalence Reproducibility of Results Risk Assessment Methods Risk Factors Sensitivity and Specificity Subtraction Technique Statistics and Numerical Data Human Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: The purpose of this study was to evaluate the role of sonographic-cytological correlation in determining which nodules should be reaspirated to reduce the false-negative rate of fine-needle aspiration biopsy (FNAB). A retrospective cohort study was performed on a database of 568 patients with 672 focal thyroid nodules. An independent two-sample t-test was used to compare the risk of malignancy according to clinical factors. We evaluated the risk stratification of malignancy according to US groupings and cytological results. Additionally, we calculated the false-negative rate of FNAB and investigated the cytological results of repeat aspiration. The malignancy rate (92.2-98.5%) was high in thyroid nodules designated "malignant" or "suspicious for papillary carcinoma" on FNAB, regardless of US features. In contrast, when focal thyroid nodules had "benign" readings on FNAB, the malignancy rate was lower for the "probably benign" US features (2.9%) than for the suspicious nodules (56.6%). The false-negative rate of FNAB was 5.8%. Repeat aspiration revealed "suspicious for malignancy" or "malignancy" results in 15 (93.8%) of 16 thyroid cancers with "benign" results on initial aspirate. This study demonstrated repeat FNAB should be performed on focal thyroid nodules with suspicious US features even when initial FNAB results are benign. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|