The European postmarketing adult Osteosarcoma Surveillance Study: characteristics of patients: a preliminary report.
The Scandinavian Sarcoma Group (SSG) registry participates in a multinational postmarketing drug surveillance study evaluating potential medication exposures (including teriparatide) in a population-based series of adult osteosarcoma cases. We present preliminary data from this study. The SSG regist...
| Publicado en: | Acta Orthopaedica (Supplement) Vol. 80; pp. 67 - 75 |
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| Autores principales: | , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Medical Journals Sweden AB
Apr2009 Supplement 334
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105399037&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105399037 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17453690 1WHY jtl: Acta Orthopaedica (Supplement) issn: 17453690 maglogo: N pubinfo: dt: Apr2009 Supplement 334 vid: 80 pid: 59195 pub: Medical Journals Sweden AB artinfo: ui: 105399037 105399037 2010363028 105399037 ppf: 67 ppct: 8 formats: fmt: @attributes: type: P tig: atl: The European postmarketing adult Osteosarcoma Surveillance Study: characteristics of patients: a preliminary report. aug: au: von Schéele B Martin RD Gilsenan AW Ceberg J Andrews EB Masica D Alvegård T affil: RTI Health Solutions, Williams House, Manchester Science Park, the United Kingdom; bscheele@rti.org sug: subj: Osteosarcoma Epidemiology Adult Aged Aged, 80 and Over Descriptive Statistics Europe Female Male Maps Middle Age Osteosarcoma Classification Osteosarcoma Drug Therapy Osteosarcoma Risk Factors Parathyroid Hormones Therapeutic Use Record Review Human Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: The Scandinavian Sarcoma Group (SSG) registry participates in a multinational postmarketing drug surveillance study evaluating potential medication exposures (including teriparatide) in a population-based series of adult osteosarcoma cases. We present preliminary data from this study. The SSG registry systematically identifies eligible cases in collaboration with regional and national cancer registries in Sweden, Norway, Denmark, Finland, and Iceland. All cases aged 2 40 years initially diagnosed in January 2004 or later with histologically confirmed osteosarcoma or 5 other prespecified types of bone sarcomas are eligible. Data were collected from the medical records. This review includes all information abstracted to date from patient records of 49 of 85 cases diagnosed between January 2004 and September 2008 (estimated to be all reported adult cases). All patients were Caucasian, mean age 59 (41-88 years), the majority were men. The most prevalent morphology subtypes were osteosarcoma NOS and chondroblastic osteosarcoma. Leg bones were the most frequent tumor site. Potential risk factors for osteosarcoma included prior history of cancer (27%), radiation treatment (24%), or prior injury or infection at the site of the tumor (14%). Site of prior radiation treatment and osteosarcoma tumor matched for 7/9 cases. One prior history of Paget's disease was reported. Treatment with teriparatide before diagnosis had not been reported. Data collected in this study present population based demographic and risk-factor data and are consistent with prior research reporting a link between radiation site and tumor site, and a possible association between osteosarcoma and prior history of cancer, and prior injury or infection at the site of the tumor. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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