The Scandinavian Sarcoma Group Skeletal Metastasis Registry: functional outcome and pain after surgery for bone metastases in the pelvis and extremities.

Background Few authors have investigated function and pain after surgical treatment of patients with bone metastases. In 1999 the Scandinavian Sarcoma Group (SSG) initiated the Skeletal Metastasis Registry as a multi-centric, prospective study to provide a scientific basis for recommendations of tre...

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Publicado en:Acta Orthopaedica (Supplement) Vol. 80; pp. 85 - 91
Autores principales: Hansen BH, Keller J, Laitinen M, Berg P, Skjeldal S, Trovik C, Nilsson J, Walloe A, Kalén A, Wedin R
Formato: research tables/charts Journal Article
Publicado: Medical Journals Sweden AB Apr2009 Supplement 334
Acceso en línea:Ver este registro en EBSCOhost
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        atl: The Scandinavian Sarcoma Group Skeletal Metastasis Registry: functional outcome and pain after surgery for bone metastases in the pelvis and extremities.
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          Hansen BH
          Keller J
          Laitinen M
          Berg P
          Skjeldal S
          Trovik C
          Nilsson J
          Walloe A
          Kalén A
          Wedin R
        affil: Dept of Orthopedic Surgery, University Hospital, Aarhus, Denmark; bhhan@as.aaa.dk
      sug:
        subj:
          Bone and Bones Pathology
          Neoplasm Metastasis
          Neoplasms Complications
          Adult
          Aged
          Aged, 80 and Over
          Clinical Assessment Tools
          Descriptive Statistics
          Female
          Functional Status
          Kaplan-Meier Estimator
          Karnofsky Performance Status
          Male
          Middle Age
          Neoplasm Metastasis Surgery
          Orthopedic Fixation Devices
          Physical Mobility
          Postoperative Pain
          Prostheses and Implants
          Reoperation
          Scandinavia
          Survival
          Treatment Outcomes
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background Few authors have investigated function and pain after surgical treatment of patients with bone metastases. In 1999 the Scandinavian Sarcoma Group (SSG) initiated the Skeletal Metastasis Registry as a multi-centric, prospective study to provide a scientific basis for recommendations of treatment. Patients and methods We have analyzed function and pain in 530 patients ( mean age 65 yr) operated on ( 599 operations) for non-spinal skeletal metastases at 9 SSG centres. 7% were operated for more than 1 metastasis. Carcinoma of the breast, prostate, kidney, and lung were the dominating sites for primary tumors. Results 25% of the patients died within 6 weeks after operation. 11% of the patients had complications. 6% had reoperation. In patients surviving more than 1 year the reoperation rate was 12%. 92% of the patients had no, light or moderate pain from metastasis at 6 weeks ( first control) and 6 months follow-up. Patients using opioids were reduced from 40% preoperative to 30% at 6 months after surgery. In patients with metastases in pelvis or lower extremity 79% were walking with or without crutches, 6 weeks and 88%, 6 months after surgery. More patients with metastases in proximal femur were mobile at 6 weeks and 6 months when treated with prosthetic replacement compared to internal fixation. Interpretation Palliative surgery for bone metastases improves function and reduce pain. Mobility is improved by surgery in patients with metastases in the pelvis or lower extremity. Prosthetic replacement seems to do better than internal fixation for metastases in the proximal femur. We need to analyze function and pain earlier than 6 weeks postoperative to investigate the benefit of surgery in patients with short time survival.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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