Selecting the transthoracic defibrillation shock directional vector based on VF amplitude improves shock success.

Introduction: Termination of ventricular fibrillation (VF) by a defibrillating shock is more likely to occur when the VF amplitude is larger. We hypothesized that a defibrillation shock would achieve higher success if the shock vector was oriented along the largest of the VF amplitudes measured simu...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 20; no. 9; pp. 1032 - 1039
Autores principales: Brooks L, Zhang Y, Dendi R, Anderson RH, Zimmerman B, Kerber RE
Formato: research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell Sep2009
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2009
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      pub: Wiley-Blackwell
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        10.1111/j.1540-8167.2009.01483.x
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        atl: Selecting the transthoracic defibrillation shock directional vector based on VF amplitude improves shock success.
      aug:
        au:
          Brooks L
          Zhang Y
          Dendi R
          Anderson RH
          Zimmerman B
          Kerber RE
        affil: Cardiovascular Center, College of Medicine, University of Iowa, Iowa City, Iowa, USA
      sug:
        subj:
          Defibrillation Methods
          Quality of Health Care
          Resuscitation, Cardiopulmonary
          Ventricular Fibrillation Prevention and Control
          Animal Studies
          Confidence Intervals
          Electrocardiography
          Funding Source
          Iowa
          Odds Ratio
          Swine
      ab: Introduction: Termination of ventricular fibrillation (VF) by a defibrillating shock is more likely to occur when the VF amplitude is larger. We hypothesized that a defibrillation shock would achieve higher success if the shock vector was oriented along the largest of the VF amplitudes measured simultaneously in 3 orthogonal ECG leads, and that this axis could be determined near-instantaneously in real time. Methods and Results: In 9 closed-chest anesthetized swine, a new directional defibrillation (DD) device was used to simultaneously measure the VF peak amplitudes displayed by 3 orthogonal pairs of defibrillation electrodes: anterior-posterior, lateral-lateral, and superior-inferior. Four shocks at each of 3 energy levels (30 Joules [J], 50 J, and 100 J) were delivered through the electrode pair measuring the largest (LA) and smallest (SA) VF peak amplitude at the time of the shock. The odds of shock success (VF termination followed by a perfusing rhythm) were 5 times more likely when shocks were delivered from the LA electrodes than the SA electrodes (odds ratio 5.10, 95% CI: 1.39, 18.79). At the intermediate energy level of 50 J, shocks delivered through the LA electrode pairs had an almost 9 times higher odds of shock success than 50 J shocks delivered through the SA electrode pairs (68.3% vs 18.9%, P = 0.002) (odds ratio 8.94, 95% CI: 2.59, 30.82). Transthoracic impedance and current did not differ for shocks delivered in the LA versus SA groups. Conclusion: Choosing the defibrillation directional vector based on the largest VF amplitude improved shock success.
      pubtype: Academic Journal
      doctype:
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      ougenre: Article
    language: English
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