From pills to programs: lessons from medicine for developing effective lifestyle interventions.
OBJECTIVE: To propose a scheme for comprehensive development and evaluation of lifestyle interventions. METHODS: We adapted the four-phase system used in drug development, the engine of progress in medicine for decades, to construct a system for developing lifestyle intervention programs. RESULTS: P...
| Publicado en: | Preventive Medicine Vol. 49; no. 1; pp. 12 - 19 |
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| Autores principales: | , , , , , |
| Formato: | clinical trial research tables/charts Journal Article |
| Publicado: |
Academic Press Inc.
Aug2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105419665&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105419665 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00917435 DP9 jtl: Preventive Medicine issn: 00917435 maglogo: N pubinfo: dt: Aug2009 vid: 49 iid: 1 pid: 735 pub: Academic Press Inc. place: Burlington, Massachusetts artinfo: ui: 105419665 2010388687 10.1016/j.ypmed.2009.03.010 NLM19289142 105419665 ppf: 12 ppct: 7 formats: tig: atl: From pills to programs: lessons from medicine for developing effective lifestyle interventions. aug: au: Rosen LJ Manor O Brody DL Engelhard D Shtarkshall RA Zucker D affil: Department of Health Promotion, School of Public Health, Tel Aviv University, Ramat Aviv, Israel. rosenl@post.tau.ac.il sug: subj: Life Style Changes In Infancy and Childhood Program Development Program Evaluation School Health Education Evaluation Adolescence Child Clinical Trials Descriptive Statistics Funding Source Handwashing Israel P-Value Human Adolescent: 13-18 years Child: 6-12 years ab: OBJECTIVE: To propose a scheme for comprehensive development and evaluation of lifestyle interventions. METHODS: We adapted the four-phase system used in drug development, the engine of progress in medicine for decades, to construct a system for developing lifestyle intervention programs. RESULTS: Phase I: The intervention is constructed and tested with a small number of individuals. Acceptability and feasibility are assessed. Evaluation is primarily qualitative. Phase II: Effectiveness on intermediate endpoints (e.g. behavior) is tested in a real field setting, with a limited number of individuals, using a before-and-after design. An iterative process of testing and refinement may be necessary. Phase III: The effectiveness of the intervention on health-related outcomes is tested, using, where possible, a randomized design. Phase IV: Large-scale implementation and penetration are assessed in other populations. Process variables and local and national health indicators are studied. The development and evaluation of our hygiene intervention, which took place in Jerusalem from 1999 to 2001, is presented as a case study. CONCLUSIONS: Adaptation of the phased system of drug development to lifestyle interventions is a conceptually simple approach to building effective, sustainable programs for community-based public health. Copyright © 2009 by Elsevier Inc. pubtype: Academic Journal doctype: clinical trial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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