Cryptococcus gattii meningoencephalitis in an immunocompetent person 13 months after exposure.
A 53-year old immunocompetent Swiss female is described who developed severe meningoencephalitis due to infection with Cryptococcus gattii 13 months following exposure on Vancouver Island, Canada. Diagnosis was based on cerebrospinal fluid (CSF) examination, i.e., positive India-ink staining, positi...
| Publicado en: | Infection Vol. 37; no. 4; pp. 370 - 374 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | case study tables/charts Journal Article |
| Publicado: |
Springer Nature
Aug2009
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105428848&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105428848 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03008126 NXO jtl: Infection issn: 03008126 maglogo: N pubinfo: dt: Aug2009 vid: 37 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105428848 2010399512 10.1007/s15010-008-8211-z NLM19390780 105428848 ppf: 370 ppct: 4 formats: fmt: @attributes: type: P tig: atl: Cryptococcus gattii meningoencephalitis in an immunocompetent person 13 months after exposure. aug: au: Georgi A Schneemann M Tintelnot K Calligaris-Maibach RC Meyer S Weber R Bosshard PP affil: Department of Medicine, University Hospital Zurich, Zurich, Switzerland. sug: subj: Amphotericin B Therapeutic Use Fluconazole Therapeutic Use Meningoencephalitis Drug Therapy Meningoencephalitis Microbiology Drainage Female Length of Stay Middle Age Switzerland Middle Aged: 45-64 years Female ab: A 53-year old immunocompetent Swiss female is described who developed severe meningoencephalitis due to infection with Cryptococcus gattii 13 months following exposure on Vancouver Island, Canada. Diagnosis was based on cerebrospinal fluid (CSF) examination, i.e., positive India-ink staining, positive latex particle agglutination, and positive culture. Species identification was performed by growth on L-canavanine-glycine-bromthymol blue medium and by sequencing of the intergenic and internal transcribed spacer regions of the rRNA genes. After initial therapy with fluconazole by which the patient did not improve, therapy was changed to amphotericin B and flucytosine and later to high-dose fluconazole and amphotericin B. Despite long-term treatment and external drainage of the CSF, the patient's condition improved only slowly. The patient was discharged after 132 days of hospitalization. pubtype: Academic Journal doctype: case study tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|