Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end-stage renal disease.

Objective: The pharmacokinetic (PK) and pharmacodynamic (PD) responses to prasugrel were compared in three studies of healthy subjects vs. those with moderate or end-stage renal impairment. Methods: Two of the three protocols were parallel-design, open-label, single dose (60-mg prasugrel) studies in...

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Publicado en:Journal of Clinical Pharmacy & Therapeutics Vol. 34; no. 5; pp. 585 - 595
Autores principales: Small DS, Wrishko RE, Ernest CS II, Ni L, Winters KJ, Farid NA, Li YG, Brandt JT, Salazar DE, Borel AG, Kles KA, Payne CD
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Oct2009
Acceso en línea:Ver este registro en EBSCOhost