Transient thrombocytosis with megathrombocytes in a case of acute myeloblastic leukemia.
Thrombocytosis is commonly seen in reactive conditions and certain neoplastic states, such as chronic myeloproliferative disorders. It is rarely seen in acute leukemia. A 12-year-old girl with acute myeloblastic leukemia (FAB M2) in remission presented with pyoderma. Her hemogram revealed anemia (Hb...
| Publicado en: | Indian Journal of Pathology & Microbiology Vol. 52; no. 1; pp. 113 - 115 |
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| Autores principales: | , , , , , , , |
| Formato: | case study Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Jan-Mar2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105444257&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105444257 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03774929 50DI jtl: Indian Journal of Pathology & Microbiology issn: 03774929 maglogo: N pubinfo: dt: Jan-Mar2009 vid: 52 iid: 1 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 105444257 NLM19136802 2010422656 10.4103/0377-4929.44992 NLM19136802 105444257 ppf: 113 ppct: 2 formats: tig: atl: Transient thrombocytosis with megathrombocytes in a case of acute myeloblastic leukemia. aug: au: Kotru M Batra M Gomber S Rusia U Kotru, Mrinalini Batra, Madhu Gomber, Sunil Rusia, Usha affil: Department of Pathology, University College of Medical Sciences and Associated Guru Teg Bahadur Hospital, New Delhi - 110 095, India sug: subj: Leukemia, Myeloid, Acute Complications Leukemia, Myeloid, Acute Pathology Thrombocytosis Pathology Anemia Etiology Child Female Pyoderma Etiology Child: 6-12 years Female ab: Thrombocytosis is commonly seen in reactive conditions and certain neoplastic states, such as chronic myeloproliferative disorders. It is rarely seen in acute leukemia. A 12-year-old girl with acute myeloblastic leukemia (FAB M2) in remission presented with pyoderma. Her hemogram revealed anemia (Hb-6.4g/dl), leucopenia (TLC - 1.2 x 109/L) and thrombocytosis (platelet count- 580 x 109/L). A peripheral blood film showed numerous abnormally large platelets with few atypical cells. The thrombocytosis subsided with the clearance of infection but atypical cells persisted. One month later, she relapsed. Cytogenetic analysis revealed variable results (trisomy 9 and deletion 3). This case has been presented because thrombocytosis is rare in AML and its appearance calls for a close follow-up. pubtype: Academic Journal doctype: case study Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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