Involvement of gene polymorphisms of the folate pathway enzymes in gene expression and anticancer drug sensitivity using the NCI-60 panel as a model.
Folate, a vitamin of the B group involved in one-carbon group metabolism, plays an important role in DNA synthesis and methylation. Several polymorphisms in the genes involved in folate uptake and biotransformations have been shown to be associated to the risk of cancer and to anticancer drug respon...
| Publicado en: | European Journal of Cancer Vol. 45; no. 13; pp. 2391 - 2402 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Pergamon Press - An Imprint of Elsevier Science
Sep2009
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| Acceso en línea: | Ver este registro en EBSCOhost |