The "portable" CDR: translating the clinical dementia rating interview into a PDA format.
The Clinical Dementia Rating (CDR) is a common rating system used in clinical trials and longitudinal research projects to rate the presence and severity of cognitive problems in Alzheimer disease and related disorders. The interview process requires training and can be time-consuming. Here, we desc...
| Publicado en: | Alzheimer Disease & Associated Disorders Vol. 23; no. 1; pp. 44 - 50 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Jan-Mar2009
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105468743&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105468743 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08930341 MZB jtl: Alzheimer Disease & Associated Disorders issn: 08930341 maglogo: N pubinfo: dt: Jan-Mar2009 vid: 23 iid: 1 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 105468743 105468743 NLM18695592 2010212039 10.1097/WAD.0b013e31817634a0 NLM18695592 PMC2798727 105468743 ppf: 44 ppct: 6 formats: tig: atl: The "portable" CDR: translating the clinical dementia rating interview into a PDA format. aug: au: Galvin JE Meuser TM Coats MA Bakal DA Morris JC Galvin, James E Meuser, Thomas M Coats, Mary A Bakal, Donald A Morris, John C affil: Alzheimer Disease Research Center, Washington University School of Medicine, 4488 ForestPark, Suite 130, St. Louis, MO 63108, USA sug: subj: Computers, Hand-Held Dementia Diagnosis Diagnosis, Computer Assisted Methods Severity of Illness Indices Algorithms Interviews Methods Reproducibility of Results Scales Software Human ab: The Clinical Dementia Rating (CDR) is a common rating system used in clinical trials and longitudinal research projects to rate the presence and severity of cognitive problems in Alzheimer disease and related disorders. The interview process requires training and can be time-consuming. Here, we describe the validity, reliability, and discriminative ability of a computer-generated CDR using a personal digital assistant format. This project used clinical data from 138 archival and live evaluations (patient and informant interviews) collected for research purposes at Washington University to develop and test a software-based system for the administration and automatic scoring of the CDR. The system was programmed for use on a hand-held computer via the Palm Operating System. We developed domain-specific algorithms to quantify and translate clinical scoring decisions for the 3 cognitive (Memory, Orientation, Judgment and Problem Solving) and the 3 functional (Community Affairs, Home and Hobbies, Personal Care) domains of the CDR. An acceptable set of algorithms were developed using data from 104 research cases, reflecting a range of impairment levels (CDR 0 to 3) and expert scoring decisions. These algorithms were then tested for accuracy in a validation sample of 34 cases. The computer-generated CDR has excellent internal consistency (Cronbach's alpha ranging from 0.94 to 0.98) and interrater reliability (intraclass correlation coefficient ranging from 0.88 to 0.96). The computer-generated CDR showed excellent discrimination between demented and nondemented cases (Area under the curve=0.95; 95% confidence interval, 0.84-1.1). The computer-generated CDR using a Palm Operating System is easy to use, valid, and reliable. The level of agreement compares favorably to published interrater reliability data for the CDR. Software-based administration and automatic scoring of the CDR is a viable alternative to paper-based methods and may be useful in research and clinical settings, especially where electronic data management and reliability in scoring are critical. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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