Predictors of change in life skills in schizophrenia after cognitive remediation.
Few studies have investigated predictors of response to cognitive remediation interventions in patients with schizophrenia. Predictor studies to date have selected treatment outcome measures that were either part of the remediation intervention itself or closely linked to the intervention with few s...
| Published in: | Schizophrenia Research Vol. 107; no. 2/3; pp. 267 - 275 |
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| Main Authors: | , , , , , , , , , |
| Format: | research Journal Article |
| Published: |
Elsevier B.V.
Feb2009
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105477906&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105477906 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09209964 3PT jtl: Schizophrenia Research issn: 09209964 maglogo: N pubinfo: dt: Feb2009 vid: 107 iid: 2/3 pid: 1004 pub: Elsevier B.V. artinfo: ui: 105477906 NLM19006657 2010223922 10.1016/j.schres.2008.10.014 NLM19006657 PMC3399665 105477906 ppf: 267 ppct: 8 formats: tig: atl: Predictors of change in life skills in schizophrenia after cognitive remediation. aug: au: Kurtz MM Seltzer JC Fujimoto M Shagan DS Wexler BE Kurtz, Matthew M Seltzer, James C Fujimoto, Marco Shagan, Dana S Wexler, Bruce E affil: Department of Psychology, Wesleyan University, Judd Hall, 207 High Street, Middletown, CT 06459, United States sug: subj: Activities of Daily Living Psychosocial Factors Rehabilitation, Cognitive Computer-Assisted Instruction Psychology Remedial Teaching Schizophrenia Rehabilitation Adult Attention Behavior Cognition Disorders Diagnosis Cognition Disorders Psychosocial Factors Female Learning Memory, Short Term Middle Age Neuropsychological Tests Statistics and Numerical Data Problem Solving Prognosis Psychological Tests Statistics and Numerical Data Psychometrics Psychomotor Performance Readability Schizophrenia Diagnosis Socialization Software Human Adult: 19-44 years Middle Aged: 45-64 years Female ab: Few studies have investigated predictors of response to cognitive remediation interventions in patients with schizophrenia. Predictor studies to date have selected treatment outcome measures that were either part of the remediation intervention itself or closely linked to the intervention with few studies investigating factors that predict generalization to measures of everyday life-skills as an index of treatment-related improvement. In the current study we investigated the relationship between four measures of neurocognitive function, crystallized verbal ability, auditory sustained attention and working memory, verbal learning and memory, and problem-solving, two measures of symptoms, total positive and negative symptoms, and the process variables of treatment intensity and duration, to change on a performance-based measure of everyday life-skills after a year of computer-assisted cognitive remediation offered as part of intensive outpatient rehabilitation treatment. Thirty-six patients with schizophrenia or schizoaffective disorder were studied. Results of a linear regression model revealed that auditory attention and working memory predicted a significant amount of the variance in change in performance-based measures of everyday life skills after cognitive remediation, even when variance for all other neurocognitive variables in the model was controlled. Stepwise regression revealed that auditory attention and working memory predicted change in everyday life-skills across the trial even when baseline life-skill scores, symptoms and treatment process variables were controlled. These findings emphasize the importance of sustained auditory attention and working memory for benefiting from extended programs of cognitive remediation. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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