Cover Image
QR Code

Thyroid and brain: review.

Thyroid hormone (TH) is a key regulatory factor of the normal brain developmental programme possibly throughout fetal and extrauterine life. In addition to its role in cellular metabolic activity, TH is critically involved in growth, development, and function of the central nervous system. Enviromen...

Full description

Published in:Turkiye Klinikleri Journal of Medical Sciences Vol. 29; no. 1; pp. 215 - 221
Main Authors: Emral R, Sayki Arslan M
Format: abstract tables/charts Journal Article
Published: Turkiye Klinikleri 2009 Feb
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105499741&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 105499741
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        13000292
        1VOP
      jtl: Turkiye Klinikleri Journal of Medical Sciences
      issn: 13000292
      maglogo: N
    pubinfo:
      dt: 2009 Feb
      vid: 29
      iid: 1
      pid: 67298
      pub: Turkiye Klinikleri
    artinfo:
      ui:
        105499741
        105499741
        2010247133
        105499741
      ppf: 215
      ppct: 6
      formats:
      tig:
        atl: Thyroid and brain: review.
      aug:
        au:
          Emral R
          Sayki Arslan M
        affil: Ankara University, Ankara, Turkey
      sug:
        subj:
          Brain
          Thyroid Gland
          Affect Drug Effects
          Behavior Drug Effects
          Brain Physiology
          Central Nervous System Physiology
          Child Development
          Deficiency Diseases Complications
          Fetal Development
          Infant Development
          Iodine Deficiency
          Motor Skills
          Thyroid Hormones Metabolism
          Vision
      ab: Thyroid hormone (TH) is a key regulatory factor of the normal brain developmental programme possibly throughout fetal and extrauterine life. In addition to its role in cellular metabolic activity, TH is critically involved in growth, development, and function of the central nervous system. Enviromental factors that interfere with thyroid function or TH action may produce deleterious effects on brain development by interfering with TH action in the developing brain. All degrees of iodine deficiency affect thyroid function of the mother and the neonate as well as the mental development of the child. Experimental studies and clinical research have clarified not only the correlation between nervous system maturation and tyhroid function during early development stages but also excess and deficient THs can cause permanent anatomo-functional alterations to the nervous system. If the TH deficiency occurs early in pregnancy, the offspring display problems in visual attention, visual processing and gross motor skills. Also the effect of THs is known on the putative neurotransmitter systems, that regulate mood and behaviour.
      pubtype: Academic Journal
      doctype:
        abstract
        tables/charts
        Journal Article
      ougenre: Article
    language: Turkish
    refInfo:
    holdings:
      @attributes:
        islocal: N