Pharmacokinetics and metabolism of idebenone in healthy male subjects.

PURPOSE: Idebenone is a synthetic analogue of ubiquinone that may be beneficial in the treatment of Friedreich's ataxia. Since in previous pharmacokinetic trials only lower doses were studied, it was the aim of this study to evaluate the pharmacokinetics of idebenone in higher doses of up to 2,250 m...

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Bibliographic Details
Published in:European Journal of Clinical Pharmacology Vol. 65; no. 5; pp. 493 - 502
Main Authors: Bodmer M, Vankan P, Dreier M, Kutz KW, Drewe J
Format: equations & formulas research tables/charts Journal Article
Published: Springer Nature May2009
Online Access:View this record in EBSCOhost