Quantitation of DNA methylation by melt curve analysis.
Background: Methylation of DNA is a common mechanism for silencing genes, and aberrant methylation is increasingly being implicated in many diseases such as cancer. There is a need for robust, inexpensive methods to quantitate methylation across a region containing a number of CpGs. We describe and...
| Publicado en: | BMC Cancer Vol. 9; pp. 123 - 124 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | Ver este registro en EBSCOhost |